User profiles for Dunja Knapp

Dunja Knapp

CRTD
Verified email at tu-dresden.de
Cited by 3640

Cells keep a memory of their tissue origin during axolotl limb regeneration

M Kragl, D Knapp, E Nacu, S Khattak, M Maden… - Nature, 2009 - nature.com
During limb regeneration adult tissue is converted into a zone of undifferentiated progenitors
called the blastema that reforms the diverse tissues of the limb. Previous experiments have …

[HTML][HTML] Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs

T Tanaka, D Knapp, K Nasmyth - Cell, 1997 - cell.com
In eukaryotic cells, firing of DNA replication origins normally does not recur until after M
phase. This characteristic is thought to be due to the properties of "initiation" proteins like Orc, …

[HTML][HTML] The axolotl genome and the evolution of key tissue formation regulators

…, AR Hastie, G Young, JG Roscito, F Falcon, D Knapp… - Nature, 2018 - nature.com
Salamanders serve as important tetrapod models for developmental, regeneration and
evolutionary studies. An extensive molecular toolkit makes the Mexican axolotl (Ambystoma …

Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration

T Gerber, P Murawala, D Knapp, W Masselink… - Science, 2018 - science.org
INTRODUCTION Axolotls (Ambystoma mexicanum) and other salamanders are the only
tetrapods that can regenerate whole limbs. During this complex process, changes in gene …

[HTML][HTML] Comparative transcriptional profiling of the axolotl limb identifies a tripartite regeneration-specific gene program

D Knapp, H Schulz, CA Rascon, M Volkmer, J Scholz… - PloS one, 2013 - journals.plos.org
Understanding how the limb blastema is established after the initial wound healing response
is an important aspect of regeneration research. Here we performed parallel expression …

The Transcription Factor Swi5 Regulates Expression of the Cyclin Kinase Inhibitor p40SIC1

D Knapp, L Bhoite, DJ Stillman… - Molecular and Cellular …, 1996 - Taylor & Francis
DNA replication in budding yeast cells depends on the activation of the Cdc28 kinase (Cdkl
of Saccharomyces cerevisiae) associated with B-type cyclins Clb1 to Clb6. Activation of the …

Connective tissue cells, but not muscle cells, are involved in establishing the proximo-distal outcome of limb regeneration in the axolotl

…, HQ Le, FFR Damanik, M Schuez, D Knapp… - …, 2013 - journals.biologists.com
During salamander limb regeneration, only the structures distal to the amputation plane are
regenerated, a property known as the rule of distal transformation. Multiple cell types are …

Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain

DA Berg, M Kirkham, A Beljajeva, D Knapp… - …, 2010 - journals.biologists.com
In contrast to mammals, salamanders and teleost fishes can efficiently repair the adult brain.
It has been hypothesised that constitutively active neurogenic niches are a prerequisite for …

Efficient gene knockin in axolotl and its use to test the role of satellite cells in limb regeneration

JF Fei, M Schuez, D Knapp… - Proceedings of the …, 2017 - National Acad Sciences
Salamanders exhibit extensive regenerative capacities and serve as a unique model in
regeneration research. However, due to the lack of targeted gene knockin approaches, it has …

[HTML][HTML] Conserved enhancers control notochord expression of vertebrate Brachyury

…, J Smolikova, HR Moran, BJ Mannion, D Knapp… - Nature …, 2023 - nature.com
The cell type-specific expression of key transcription factors is central to development and
disease. Brachyury/T/TBXT is a major transcription factor for gastrulation, tailbud patterning, …