A proximity-dependent biotinylation map of a human cell

…, JP Lambert, É Coyaud, SWT Cheung, D Rajendran… - Nature, 2021 - nature.com
Compartmentalization is a defining characteristic of eukaryotic cells, and partitions distinct
biochemical processes into discrete subcellular locations. Microscopy 1 and biochemical …

[PDF][PDF] Phenotypic and interaction profiling of the human phosphatases identifies diverse mitotic regulators

…, AO Veri, JDR Knight, D Rajendran… - Cell reports, 2016 - cell.com
Reversible phosphorylation is a fundamental regulatory mechanism, intricately coordinated
by kinases and phosphatases, two classes of enzymes widely disrupted in human disease. …

The GATOR–Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids

GG Hesketh, F Papazotos, J Pawling, D Rajendran… - Science, 2020 - science.org
The mechanistic target of rapamycin complex 1 (mTORC1) couples nutrient sufficiency to
cell growth. mTORC1 is activated by exogenously acquired amino acids sensed through the …

A proximity biotinylation map of a human cell

…, JP Lambert, É Coyaud, SWT Cheung, D Rajendran… - BioRxiv, 2019 - biorxiv.org
Compartmentalization is an essential characteristic of eukaryotic cells, ensuring that cellular
processes are partitioned to defined subcellular locations. High throughput microscopy 1 …

TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex

N Merritt, K Garcia, D Rajendran, ZY Lin, X Zhang… - Elife, 2021 - elifesciences.org
Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma that metastasizes early in
its clinical course and lacks an effective medical therapy. The TAZ-CAMTA1 and YAP-TFE3 …

[PDF][PDF] Structural basis for auto-inhibition of the NDR1 kinase domain by an atypically long activation segment

…, AL Couzens, CM Templeton, D Rajendran… - Structure, 2018 - cell.com
The human NDR family kinases control diverse aspects of cell growth, and are regulated
through phosphorylation and association with scaffolds such as MOB1. Here, we report the …

Author Correction: A proximity-dependent biotinylation map of a human cell

…, JP Lambert, É Coyaud, SWT Cheung, D Rajendran… - Nature, 2022 - nature.com
In the version of this Article initially published, we omitted in the introductory paragraph a
reference to a paper that reported the BioID profiles of 18 subcellular markers and …

A proximity-dependent biotinylation map of a human cell: An interactive web resource

…, J Lambert, É Coyaud, SW Cheung, D Rajendran… - 2019 - europepmc.org
Compartmentalization is a defining characteristic of eukaryotic cells, partitioning cellular
processes into discrete subcellular locations. High throughput microscopy 1 and biochemical …

TAZ-CAMTA1 and YAP-TFE3 modulate the basal TAZ/YAP transcriptional program by recruiting the ATAC histone acetyltransferase complex

N Merritt, K Garcia, D Rajendran, ZY Lin, X Zhang… - bioRxiv, 2020 - biorxiv.org
Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma that metastasizes early and
lacks an effective medical therapy. The TAZ-CAMTA1 and YAP-TFE3 fusion proteins are …

[BOOK][B] Identification of Novel Regulators of Numb Alternative Splicing

D Rajendran - 2014 - search.proquest.com
Alternative splicing (AS) is a post-transcriptional mechanism resulting in the production of
multiple mRNA and protein isoforms from a single gene. The endocytic adaptor protein Numb …