We describe a technology, the NanoString nCounter gene expression system, which captures
and counts individual mRNA transcripts. Advantages over existing platforms include direct …

Resolving the spatial distribution of RNA and protein in tissues at subcellular resolution is a
challenge in the field of spatial biology. We describe spatial molecular imaging, a system …

Digital Spatial Profiling (DSP) is a method for highly multiplex spatial profiling of proteins or
RNAs suitable for use on formalin-fixed, paraffin-embedded (FFPE) samples. The approach …

Spatial Molecular Imager (SMI) is an automated microscope imaging system with microfluidic
reagent cycling, for high-plex, spatial in-situ detection of multiomic targets (RNA and protein…

We present two new microfabricated cantilever-beam force transducers. The transducers
were fabricated from thin silicon-nitride films, and were used respectively to measure forces …

Silkworm cocoon silk and spider major ampullate (drag line) silk exhibit macroscopic tensile
properties that, while impressive in the context of polymer fibers, are highly variable. The …

Transmitted polarized light microscopy is used to identify a liquid crystalline phase both in
natural silk secretions (from spiders, silkworms and aquatic insect larvae) and in reconstituted …

Thick filaments are generally thought to be effectively inextensible. Here we use novel
nanofabricated cantilevers to carry out the first direct force-elongation measurements on single …

The spatial interactions between the immune system and tumor cells greatly influence antitumoral
immunity. Characterization of immune cell composition and infiltration within the tumor …

In the version of this article initially published, in paragraph 7, beginning with line 2, the author
incorrectly stated that “genes and promoters” were to be used; the line should have read “…