CTCF-dependent chromatin boundaries formed by asymmetric nucleosome arrays with decreased linker length

CT Clarkson, EA Deeks, R Samarista… - Nucleic acids …, 2019 - academic.oup.com
The CCCTC-binding factor (CTCF) organises the genome in 3D through DNA loops and in
1D by setting boundaries isolating different chromatin states, but these processes are not well …

D-region electron distributions in middle latitudes deduced from the reflexion of long radio waves

DG Deeks - Proceedings of the Royal Society of London …, 1966 - royalsocietypublishing.org
A method of full-wave analysis is used to compute the theoretical values of reflexion and
conversion coefficients of long and very long radio waves incident on a horizontally stratified …

[HTML][HTML] Impact of pre-existing chronic viral infection and reactivation on the development of long COVID

…, PY Hsue, JD Kelly, JN Martin, SG Deeks… - MedRxiv, 2022 - ncbi.nlm.nih.gov
… EBV reactivation (early antigen-D [EA-D] IgG positivity) or high nuclear antigen IgG levels,
but not with ongoing EBV viremia. Evidence of EBV reactivation (EA-D IgG) was most strongly …

Interpreting results and drawing conclusions

…, JJ Deeks, P Glasziou, EA Akl… - … systematic reviews of …, 2019 - Wiley Online Library
This chapter addresses first one of the key aspects of interpreting findings that is also
fundamental in completing a ‘Summary of findings’ table: the certainty of evidence related to each …

Prospective evaluation of criteria for microbiological diagnosis of prosthetic-joint infection at revision arthroplasty

BL Atkins, N Athanasou, JJ Deeks… - Journal of clinical …, 1998 - Am Soc Microbiol
A prospective study was performed to establish criteria for the microbiological diagnosis of
prosthetic joint infection at elective revision arthroplasty. Patients were treated in a …

[HTML][HTML] Chronic viral coinfections differentially affect the likelihood of developing long COVID

…, JD Kelly, JN Martin, SG Deeks… - The Journal of …, 2023 - Am Soc Clin Investig
… In order to determine the independent associations among demographic factors, preexisting
medical conditions, and EBNA and EA-D IgG results with LC and in those with specific LC …

International AIDS Society global scientific strategy: towards an HIV cure 2016

SG Deeks, SR Lewin, AL Ross, J Ananworanich… - Nature medicine, 2016 - nature.com
Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a
global population of more than 35 million people living with HIV, there is intense interest in …

[PDF][PDF] Multiple origins of virus persistence during natural control of HIV infection

…, T Schacker, F Maldarelli, SH Hughes, SG Deeks… - Cell, 2016 - cell.com
Targeted HIV cure strategies require definition of the mechanisms that maintain the virus.
Here, we tracked HIV replication and the persistence of infected CD4 T cells in individuals with …

[HTML][HTML] HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study

…, SA Yukl, JN Blankson, T Liegler, SG Deeks - PLoS …, 2017 - journals.plos.org
Background It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead
to long-term ART-free HIV remission or cure. As a result, we studied 2 individuals recruited …

[PDF][PDF] Identification of genetically intact HIV-1 proviruses in specific CD4+ T cells from effectively treated participants

…, D Douek, R Fromentin, N Chomont, SG Deeks… - Cell reports, 2017 - cell.com
Latent replication-competent HIV-1 persists in individuals on long-term antiretroviral therapy
(ART). We developed the Full-Length Individual Proviral Sequencing (FLIPS) assay to …