User profiles for E. A. Heath-Heckman

Elizabeth Heath-Heckman

Integrative Biology; Microbiology and Molecular Genetics, Michigan State University
Verified email at msu.edu
Cited by 1040

Previously unrecognized stages of species‐specific colonization in the mutualism between Xenorhabdus bacteria and Steinernema nematodes

…, KE Murfin, EA HeathHeckman… - Cellular …, 2013 - Wiley Online Library
The specificity of a horizontally transmitted microbial symbiosis is often defined by molecular
communication between host and microbe during initial engagement, which can occur in …

The chemistry of negotiation: rhythmic, glycan-driven acidification in a symbiotic conversation

…, E Koch, EAC Heath-Heckman… - Proceedings of the …, 2015 - National Acad Sciences
Glycans have emerged as critical determinants of immune maturation, microbial nutrition,
and host health in diverse symbioses. In this study, we asked how cyclic delivery of a single …

The secret languages of coevolved symbioses: insights from the Euprymna scolopes–Vibrio fischeri symbiosis

M McFall-Ngai, EAC Heath-Heckman, AA Gillette… - Seminars in …, 2012 - Elsevier
Recent research on a wide variety of systems has demonstrated that animals generally
coevolve with their microbial symbionts. Although such relationships are most often established …

Squid-derived chitin oligosaccharides are a chemotactic signal during colonization by Vibrio fischeri

…, CA Brennan, EAC Heath-Heckman… - Applied and …, 2012 - Am Soc Microbiol
Chitin, a polymer of N-acetylglucosamine (GlcNAc), is noted as the second most abundant
biopolymer in nature. Chitin serves many functions for marine bacteria in the family …

The metronome of symbiosis: interactions between microbes and the host circadian clock

EAC Heath-Heckman - 2016 - academic.oup.com
… Elizabeth AC Heath-Heckman Elizabeth AC Heath-Heckman … by bacterial symbionts
was being used as a circadian cue (Heath-Heckman et al. 2013). This was the first instance of …

Leveraging short-read sequencing to explore the genomics of sepiolid squid

E Heath-Heckman, MK Nishiguchi - Integrative and Comparative …, 2021 - academic.oup.com
Due to their large size (∼3–5 Gb) and high repetitive content, the study of cephalopod
genomes has historically been problematic. However, with the recent sequencing of several …

[HTML][HTML] First paleoproteome study of fossil fish otoliths and the pristine preservation of the biomineral crystal host

…, AR Vieira, U Radwańska, EAC Heath-Heckman… - Scientific Reports, 2023 - nature.com
Otoliths are calcium carbonate components of the stato-acoustical organ responsible for
hearing and maintenance of the body balance in teleost fish. During their formation, control over…

Persistent interactions with bacterial symbionts direct mature-host cell morphology and gene expression in the squid-vibrio symbiosis

…, EJ Koch, A El Filali, L Zhou, EAC Heath-Heckman… - …, 2018 - Am Soc Microbiol
In horizontally transmitted symbioses, structural, biochemical, and molecular features both
facilitate host colonization by specific symbionts and mediate their persistent carriage. In the …

[HTML][HTML] Transcriptional profiling of identified neurons in leech

E Heath-Heckman, S Yoo, C Winchell, M Pellegrino… - BMC genomics, 2021 - Springer
Background While leeches in the genus Hirudo have long been models for neurobiology,
the molecular underpinnings of nervous system structure and function in this group remain …

Characterization of the cell polarity gene crumbs during the early development and maintenance of the squid–vibrio light organ symbiosis

SM Peyer, EAC Heath-Heckman… - Development genes and …, 2017 - Springer
The protein Crumbs is a determinant of apical–basal cell polarity and plays a role in
apoptosis of epithelial cells and their protection against photodamage. Using the squid–vibrio …