Genome-wide association study identifies 30 loci associated with bipolar disorder

…, H Nguyen, CM Nievergelt, AN Adolfsson, EA Nwulia… - Nature …, 2019 - nature.com
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …

Genome-wide association study of bipolar disorder in European American and African American individuals

…, C Nievergelt, J Nurnberger, EA Nwulia… - Molecular …, 2009 - nature.com
To identify bipolar disorder (BD) genetic susceptibility factors, we conducted two genome-wide
association (GWA) studies: one involving a sample of individuals of European ancestry (…

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

…, T Novák, JI Nurnberger Jr, EA Nwulia… - Human molecular …, 2016 - academic.oup.com
Bipolar disorder (BD) is a genetically complex mental illness characterized by severe
oscillations of mood and behaviour. Genome-wide association studies (GWAS) have identified …

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants

…, W Coryell, J Rice, WB Lawson, EA Nwulia… - Molecular …, 2013 - nature.com
We conducted a systematic study of top susceptibility variants from a genome-wide
association (GWA) study of bipolar disorder to gain insight into the functional consequences of …

Singleton deletions throughout the genome increase risk of bipolar disorder

…, T Foroud, W Sheftner, WB Lawson, EA Nwulia… - Molecular …, 2009 - nature.com
An overall burden of rare structural genomic variants has not been reported in bipolar disorder
(BD), although there have been reports of cases with microduplication and microdeletion. …

[HTML][HTML] Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes

…, CM Nievergelt, JI Nurnberger Jr, EA Nwulia… - PLoS …, 2011 - journals.plos.org
Although a highly heritable and disabling disease, bipolar disorder's (BD) genetic variants
have been challenging to identify. We present new genotype data for 1,190 cases and 401 …

[HTML][HTML] Poor CD4 count is a predictor of untreated depression in human immunodeficiency virus-positive African-Americans

…, HN Le, S Kapetanovic, EA Nwulia - World journal of …, 2016 - ncbi.nlm.nih.gov
AIM: To determine if efforts to improve antiretroviral therapy (ART) adherence minimizes the
negative impact of depression on human immunodeficiency virus (HIV) outcomes. …

Ethnic disparities in the perception of ethical risks from psychiatric genetic studies

EA Nwulia, MM Hipolito, S Aamir… - American Journal of …, 2011 - Wiley Online Library
To examine if ethnic differences in concerns about unfavorable consequences from psychiatric
genetic studies, existing between non‐Hispanic Black and White populations, persist …

[HTML][HTML] Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder

…, K Ishizuka, AS Sawa, EA Nwulia - Translational …, 2018 - nature.com
Nwulia, one of co-authors of this paper), using the Diagnostic Interview for Genetic
Studies, Version 4 (DIGS 4.0), which we previously used for the diagnosis of BD in genome-wide …

[HTML][HTML] Apo E4 alleles and impaired olfaction as predictors of Alzheimer's disease

…, TO Obisesan, KF Manaye, EA Nwulia - Clinical and …, 2017 - ncbi.nlm.nih.gov
… Funding support for olfactory testing, and for the enrollment and neuropsychological testing
of the control subjects is through USPHS grant MH-091460 (PI, Nwulia). This publication …