User profiles for E. L. Woodahl

Erica Woodahl

University of Montana
Verified email at umontana.edu
Cited by 1254

PharmVar GeneFocus: CYP2C19

…, J Duconge, MTM Lee, EL Woodahl… - Clinical …, 2021 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele nomenclature
for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation impacts the …

PharmVar GeneFocus: CYP2C9

…, M Rodrigues Botton, EL Woodahl… - Clinical …, 2021 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele nomenclature
for the polymorphic human CYP2C9 gene. Genetic variation within the CYP2C9 gene …

[PDF][PDF] The role of MDR1 genetic polymorphisms in interindividual variability in P-glycoprotein expression and function

EL Woodahl, RJY Ho - Current drug metabolism, 2004 - academia.edu
The human multidrug resistance gene (MDR1), spanning greater than 200 kb, encodes for
the ATP-dependent membrane efflux transporter, P-glycoprotein (Pgp). Significant progress …

[HTML][HTML] Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model

…, K Patterson, S McGee, R Dalton, EL Woodahl… - Genetics in …, 2019 - Elsevier
Purpose Genotyping CYP2D6 is important for precision drug therapy because the enzyme it
encodes metabolizes approximately 25% of drugs, and its activity varies considerably …

Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity

…, A Gaedigk, KE Thummel, EL Woodahl - Clinical and …, 2020 - Wiley Online Library
The cytochrome P450 2D6 ( CYP 2D6) gene locus is challenging to accurately genotype
due to numerous single nucleotide variants and complex structural variation. Our goal was to …

Pharmacogenetics in American Indian populations: analysis of: CYP2D6:: CYP3A4:: CYP3A5:, and: CYP2C9: in the Confederated Salish and Kootenai Tribes

…, P Beatty, KE Thummel, EL Woodahl - Pharmacogenetics …, 2013 - journals.lww.com
Objectives Cytochrome P450 enzymes play a dominant role in drug elimination and variation
in these genes is a major source of interindividual differences in drug response. Little is …

[HTML][HTML] Transfer learning enables prediction of CYP2D6 haplotype function

…, A Gaedigk, RB Altman, EL Woodahl - PLoS Computational …, 2020 - journals.plos.org
Cytochrome P450 2D6 (CYP2D6) is a highly polymorphic gene whose protein product
metabolizes more than 20% of clinically used drugs. Genetic variations in CYP2D6 are …

Ethical issues in developing pharmacogenetic research partnerships with American Indigenous communities

BB Boyer, D Dillard, EL Woodahl… - Clinical …, 2011 - Wiley Online Library
Pharmacogenetic research offers the potential to improve the safety and efficacy of drug
prescribing. Assuring that the benefits of this research reach indigenous and other medically …

Gentamicin-induced ototoxicity and nephrotoxicity vary with circadian time of treatment and entail separate mechanisms

MA Blunston, A Yonovitz, EL Woodahl… - Chronobiology …, 2015 - Taylor & Francis
The aminoglycoside antibiotic gentamicin can cause both ototoxicity and nephrotoxicity, the
severity of which varies with circadian time of daily treatment. However, it is not yet resolved …

Cytochrome P450 genetic variation associated with tamoxifen biotransformation in American Indian and Alaska native people

…, KE Thummel, EL Woodahl - Clinical and …, 2018 - Wiley Online Library
Despite evidence that pharmacogenetics can improve tamoxifen pharmacotherapy, there are
few studies with American Indian and Alaska Native (AIAN) people. We examined variation …