Retrotransposable elements are deleterious at many levels, and the failure of host
surveillance systems for these elements can thus have negative consequences. However, the …

Cancer genomes often harbor hundreds of somatic DNA rearrangement junctions, many of
which cannot be easily classified into simple (eg, deletion) or complex (eg, chromothripsis) …

LINE-1s are active human DNA parasites that are agents of genome dynamics in evolution
and disease. These streamlined elements require host factors to complete their life cycles, …

10.7554/eLife.30094.001 Long Interspersed Nuclear Element-1 (LINE-1, L1) is a mobile genetic
element active in human genomes. L1-encoded ORF1 and ORF2 proteins bind L1 RNAs…

… Adney et al. describe the complete and comprehensive codon substitution mutagenesis
of human … We then compared read counts, as previously described (Adney 2018). …

In this Article, owing to a conceptual error, some of the data points shown in the graphs
corresponded to the means±1 standard deviation, rather than the actual data points. The figure …

Retrotransposable elements (RTEs) are deleterious at multiple levels, and failure of host
surveillance systems can thus have negative consequences. However, the contribution of RTE …

Cancer genomes often harbor hundreds of somatic DNA rearrangement junctions, many of
which cannot be easily classified into simple (eg deletion, translocation) or complex (eg …

In the absence of an exogenous ligand, the hemoglobins from the cyanobacteria Synechocystis
sp. PCC 6803 and Synechococcus sp. PCC 7002 coordinate the heme group with two …

Long Interspersed Nuclear Element-1 (LINE-1, L1) is the only autonomous active transposable
element in the human genome. In general, we strive for molecular level understanding of …