Analysis of potential drug‐drug interactions in medical intensive care unit patients

…, GWK Hugenholtz, EM Kuck… - … : The Journal of …, 2014 - Wiley Online Library
Objective To describe the frequency and type of potential drug‐drug interactions ( pDDI s) in
a general intensive care unit (ICU) and to make recommendations to improve the …

[HTML][HTML] Clinically relevant potential drug-drug interactions in intensive care patients: A large retrospective observational multicenter study

…, M Duyvendak, A Karakus, M Sigtermans, EM Kuck… - Journal of Critical …, 2021 - Elsevier
Purpose Potential drug-drug interactions (pDDIs) may harm patients admitted to the Intensive
Care Unit (ICU). Due to the patient's critical condition and continuous monitoring on the ICU…

[HTML][HTML] Development of diagnostic prediction tools for bacteraemia caused by third-generation cephalosporin-resistant enterobacteria in suspected bacterial …

…, BC van Hees, JAJW Kluytmans, EM Kuck… - Clinical microbiology …, 2018 - Elsevier
Objectives Current guidelines for the empirical antibiotic treatment predict the presence of
third-generation cephalosporin-resistant enterobacterial bacteraemia (3GCR-E-Bac) in case …

The effect of computerised decision support alerts tailored to intensive care on the administration of high-risk drug combinations, and their monitoring: a cluster …

…, DEM van Balen, PF Schutte, MJ Sigtermans, EM Kuck… - The Lancet, 2024 - thelancet.com
Background Drug–drug interactions (DDIs) can harm patients admitted to the intensive care
unit (ICU). Yet, clinical decision support systems (CDSSs) aimed at helping physicians …

Troglitazone. Is it all over?

LJ Wagenaar, EM Kuck, JBL Hoekstra - The Netherlands Journal of …, 1999 - Elsevier
In January 1997 a drug from a new pharmacological class, the thiazolidinediones, became
available: troglitazone. Troglitazone indirectly enhances peripheral insulin sensitivity. In this …

[HTML][HTML] Improving medication safety in the Intensive Care by identifying relevant drug-drug interactions-Results of a multicenter Delphi study

…, M Duyvendak, A Karakus, M Sigtermans, EM Kuck… - Journal of critical …, 2020 - Elsevier
Purpose Drug-drug interactions (DDIs) may cause adverse outcomes in patients admitted to
the Intensive Care Unit (ICU). Computerized decision support systems (CDSSs) may help …

A tailored implementation strategy to reduce the duration of intravenous antibiotic treatment in community-acquired pneumonia: a controlled before-and-after study

…, MH Emmelot-Vonk, EM Kuck… - European journal of …, 2014 - Springer
We previously showed that 40 % of clinically stable patients hospitalised for community-acquired
pneumonia (CAP) are not switched to oral therapy in a timely fashion because of …

Tissue concentrations after a single-dose, orally administered ofloxacin in patients with diabetic foot infections

EM Kuck, KP Bouter, JBL Hoekstra… - Foot & ankle …, 1998 - journals.sagepub.com
We studied the penetration of orally administered ofloxacin at the site of diabetes-related
foot infections in patients with a planned debridement of the lesion. A total of nine patients …

Acute delirium, probably precipitated by clarithromycin

AH Pijlman, EM Kuck, EP Van Puijenbroek… - Nederlands Tijdschrift …, 2001 - europepmc.org
Clarithromycin is a relatively new antibiotic with many applications. Its frequent use explains
why side-effects previously reported seldom now become clear. Two patients, a man aged …

[PDF][PDF] Severe neurological symptoms following synthetic cannabinoid intoxication

…, LC Wejden, NA Stienstra, EM Kuck… - … Netherlands Journal of …, 2017 - njmonline.nl
Synthetic cannabinoids are becoming increasingly popular as substances of abuse.
However, in the Netherlands synthetic cannabinoid intoxications are rare. We report a 16-year-old …