Dynamic modelling has considerably improved our understanding of complex molecular
mechanisms. Ordinary differential equations (ODEs) are the most detailed and popular …

… effects can be neglected, but in the ∼1 fl volume of the spine head the number of CaMKII
holoenzymes is considerably finite - an average of 30 are seen in electron microscopy (EM) …

An important task for many if not all the scientific domains is efficient knowledge integration,
testing and codification. It is often solved with model construction in a controllable …

Mono-, di- and trimethylated states of particular histone lysine residues are selectively found
in different regions of chromatin, thereby implying specialized biological functions for these …

Dynamic modelling has significantly improved our understanding of the complex molecular
mechanisms underpinning neurobiological processes. The detailed mechanistic insights …

Polycomb Repressive Complex 2 (PRC2) regulates key developmental genes in embryonic
stem (ES) cells and during development. Here we show that Jarid2/Jumonji, a protein …

Cutaneous T-cell lymphomas (CTCL) are a heterogenous group of non-Hodgkin’s lymphomas
of skin-trafficking T lymphocytes (Diamandidou et al., 1996). CTCL patients often suffer …

A six-step synthesis of xanthohumol (1a) and its d3-derivative (1b) from easily accessible
naringenin is reported. The prenyl side chain was introduced by Mitsunobu reaction followed …

… -em)] : [thin space (1/6-em)] Me-O ratio drops significantly indicating passivation, primarily
in the form of TiO 2 . It should be noted that the chemistry of Alloy III is proved to be chemically …

Pruritus is one of the cardinal symptoms found in patients with leukemic cutaneous T cell
lymphoma (CTCL). The nature of the pruritus experienced by CTCL patients is complex, …