Background: Remote-access techniques have been described over the recent years as a
method of removing the thyroid gland without an incision in the neck. However, there is …

Tocilizumab (TCZ) is the first humanized anti-interleukin-6 (IL-6) receptor monoclonal antibody
approved for the treatment of patients with rheumatoid arthritis (RA), Castleman’s disease…

… d, e, Increased telomere dysfunction in S6KD WI-38 cells. TIFs were detected (d) by co-localization
of γ-H2AX and telomeres, and cells with at least five TIFs were scored (e). Data …

… In control cells, TNF-α treatment led to inducible expression of NF-κB target genes, as
expected (Figure 3E). The time course of this expression varied for specific genes, consistent with …

When viruses infect cells, they almost invariably cause metabolic changes in the infected
cell as well as in several host cell types that react to the infection. Such metabolic changes …

Background: The use of the Veress needle in laparoscopy to create the pneumoperitoneum
has inherent risks; it may cause vascular and visceral injuries. The open technique is …

… ), and CTFα and CTFβ (F) were quantified and normalized against hAPP levels (E and F),
and the ratio between shAPPα and shAPPβ was calculated (E). Data are mean ± SEM of …

Hypothesis The technique of thyroidectomy has undergone little change in several decades.
The harmonic scalpel, using ultrasonic frictional heating to ligate vessels, is widely used in …

The Sir2 chromatin regulatory factor links maintenance of genomic stability to life span
extension in yeast. The mammalian Sir2 family member SIRT6 has been proposed to have …

An aged circulatory environment can activate microglia, reduce neural precursor cell activity
and impair cognition in mice. We hypothesized that brain endothelial cells (BECs) mediate …