Identification of drug targets and mechanism of action (MoA) for new and uncharacterized
anticancer drugs is important for optimization of treatment efficacy. Current MoA prediction …

Objective The F irst E pisode of P sychosis ( FEP ) represents a period of heightened risk for
aggression. However, it is not known whether this risk is significantly altered following …

It is a common observation that postmortem examination may reveal extensive atherosclerotic
changes in the coronary arteries of the hearts of persons who have shown no marked …

Aims N ational EDEN aims to evaluate the implementation and impact on key outcomes of
somewhat differently configured E arly I ntervention S ervices ( EIS ) across sites in E ngland …

Context During the past 2 decades, a major transition in the clinical characterization of psychotic
disorders has occurred. The construct of a clinical high-risk (HR) state for psychosis has …

… This study used a matched case–control method using electronic primary care records.
Stepwise conditional logistic regression modelling investigated 42 potential predictors including …

… Similarity matrix used in benchmarking of the Drug E-Rank algorithm (based on the CTRPv2
… Similarity matrix used in benchmarking of the Drug E-Rank algorithm (based on the NCI60 …

The field of atlas-based organ segmentation is multifaceted and has a long history. The
selection, or creation, of the atlas is itself a rich area of research; the results of segmentation …

… Eligible participants were identified by clinical studies officers from the UK Mental Health
Research Network who reviewed electronic case records for history of auditory hallucinations …

2001). It has been argued that a similar process, namely social shame and fear of discovery,
may also underpin avoidance in psychosis (Birchwood et al, 2000b). In a similar vein, the …