Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB) Report of the consortium on DLB international workshop
Recent neuropathologic autopsy studies found that 15 to 25% of elderly demented patients
have Lewy bodies (LB) in their brainstem and cortex, and in hospital series this may …
have Lewy bodies (LB) in their brainstem and cortex, and in hospital series this may …
[HTML][HTML] A comprehensive review of genetic association studies
JN Hirschhorn, K Lohmueller, E Byrne… - Genetics in …, 2002 - nature.com
Most common diseases are complex genetic traits, with multiple genetic and environmental
components contributing to susceptibility. It has been proposed that common genetic variants…
components contributing to susceptibility. It has been proposed that common genetic variants…
Psychophysiology and adaptive automation
EA Byrne, R Parasuraman - Biological psychology, 1996 - Elsevier
… For example, a recent study (Byrne, 1993) examined the psychophysiological responses of
42 subjects, aged 18-… We also thank Gayle Byrne and Robert Molloy for editorial comments. …
42 subjects, aged 18-… We also thank Gayle Byrne and Robert Molloy for editorial comments. …
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Genome-wide detection and characterization of positive selection in human populations
With the advent of dense maps of human genetic variation, it is now possible to detect positive
natural selection across the human genome. Here we report an analysis of over 3 million …
natural selection across the human genome. Here we report an analysis of over 3 million …
Ego4d: Around the world in 3,000 hours of egocentric video
We introduce Ego4D, a massive-scale egocentric video dataset and benchmark suite. It offers
3,670 hours of daily-life activity video spanning hundreds of scenarios (household, outdoor…
3,670 hours of daily-life activity video spanning hundreds of scenarios (household, outdoor…
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
Major depression is a debilitating psychiatric illness that is typically associated with low
mood and anhedonia. Depression has a heritable component that has remained difficult to …
mood and anhedonia. Depression has a heritable component that has remained difficult to …
[HTML][HTML] Rivastigmine for dementia associated with Parkinson's disease
…, D Aarsland, A Albanese, EJ Byrne… - … England Journal of …, 2004 - Mass Medical Soc
Background Cholinergic deficits are prominent in patients who have dementia associated
with Parkinson's disease. We investigated the effects of the dual cholinesterase inhibitor …
with Parkinson's disease. We investigated the effects of the dual cholinesterase inhibitor …
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …
Genome-wide association study identifies 30 loci associated with bipolar disorder
…, JMW Pavlides, M Trzaskowski, EM Byrne… - Nature …, 2019 - nature.com
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …