Nano-domains are sub-light-diffraction-sized heterogeneous areas in the plasma membrane
of cells, which are involved in cell signalling and membrane trafficking. Throughout the last …

Recent studies have shown that Abs that target the cell-surface enzyme CD73 (ecto-5′-nucleotidase)
reduce growth of primary tumors and metastasis in syngenic mice by inhibiting …

Tropoelastin, the precursor of elastin, undergoes a rapid monomer to multimer association
in an inverse temperature transition. This association culminates in the rapid formation of …

Here we describe a novel surface sampling technique termed pressurized liquid extraction
surface analysis (PLESA), which in combination with a dedicated high-resolution shotgun …

DNA methylation is important for gene expression and alterations in DNA methylation are
involved in the development and progression of cancer and other major diseases. Analysis of …

Small interfering RNAs (siRNA) have enabled novel, specific, and efficient treatment of
diseases, including cancer. To obtain sufficient and well-controlled intracellular delivery, a drug …

Quantum dots (QDs) have long promised to revolutionize fluorescence detection to include
even applications requiring simultaneous multi-species detection at single molecule …

Quantum dots are available in a range of spectrally separated emission colors and with a
range of water-stabilizing surface coatings that offers great flexibility for enabling bio-specificity…

Fine tuning of urine concentration occurs in the renal collecting duct in response to circulating
levels of arginine vasopressin (AVP). AVP stimulates intracellular cAMP production, which …

We present the influence of treating progeroid fibroblasts with two modified antisense
oligonucleotides (ONs) on the nuclear envelope. Two modified ONs were designed to block …