The International Human Epigenome Consortium (IHEC) coordinates the generation of a
catalog of high-resolution reference epigenomes of major primary human cell types. The …

Urothelial bladder cancer (UBC) is heterogeneous at the clinical, pathological and genetic
levels. Tumor invasiveness (T) and grade (G) are the main factors associated with outcome …

… van der Keur c , Lars Dyrskjot e , Irene Lurkin c , Marcel Vermeij c , Alfredo Carrato f , Josep
Lloreta g h , José A. Lorente i , Enrique Carrillo-de Santa Pau a , Roy G. Masius c , Manolis …

… We aimed at clarifying GATA6 function in PDAC. … ) Luciferase-based reporter assay showing
the activity of an E-cadherin reporter in HEK293 cells transfected with empty vector (blue) or …

Background Urothelial bladder cancer is a highly heterogeneous disease. Cancer cell lines
are useful tools for its study. This is a comprehensive genomic characterization of 40 …

Although Burkitt lymphomas and follicular lymphomas both have features of germinal center
B cells, they are biologically and clinically quite distinct. Here we performed whole-genome …

c-MYC oncogene is deregulated in most human tumours. Histone marks associated with
transcriptionally active genes define high-affinity c-MYC targets. The mechanisms involved in …

Although eukaryotic cells express a wide range of alternatively spliced transcripts, it is not
clear whether genes tend to express a range of transcripts simultaneously across cells, or …

Neutrophils are short-lived blood cells that play a critical role in host defense against infections.
To better comprehend neutrophil functions and their regulation, we provide a complete …

… e Same as panel d but for HVPs that map to gene bodies. HVPs at gene bodies were defined
as CpGs annotated to body and 3′ UTR, according to the 450 K array annotation manifest…