User profiles for E. Denisenko

Elena Denisenko

Research Fellow, Systems Biology and Genomics, Harry Perkins Institute of Medical …
Verified email at perkins.org.au
Cited by 1740

An atlas of human long non-coding RNAs with accurate 5′ ends

…, N Bertin, OJL Rackham, J Gough, E Denisenko… - Nature, 2017 - nature.com
… In addition, while most e-lncRNA TIRs are bidirectionally transcribed, as previously described
10 (Supplementary Note 5), we also identified a subset of unidirectional e-lncRNAs which …

[HTML][HTML] Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows

E Denisenko, BB Guo, M Jones, R Hou, L De Kock… - Genome biology, 2020 - Springer
… c–e Whole kidneys were flash frozen using an isopentane bath − 30 C and then stored at
− 80 C. Three different nuclei preparation methods were tested using either fluorescently …

[HTML][HTML] Predicting cell-to-cell communication networks using NATMI

R Hou, E Denisenko, HT Ong, JA Ramilowski… - Nature …, 2020 - nature.com
e Compares the top 10 communicating cell type pairs identified in a–d. … e The distribution
of ranks of plasma-membrane ligand mediated outgoing edges. f The distribution of ranks of …

Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC

…, NA Mellett, P Timpson, M Jones, E Denisenko… - Science …, 2023 - science.org
The incidence of hepatocellular carcinoma (HCC) is rapidly rising largely because of increased
obesity leading to nonalcoholic steatohepatitis (NASH), a known HCC risk factor. There …

scMatch: a single-cell gene expression profile annotation tool using reference datasets

R Hou, E Denisenko, ARR Forrest - Bioinformatics, 2019 - academic.oup.com
Motivation Single-cell RNA sequencing (scRNA-seq) measures gene expression at the
resolution of individual cells. Massively multiplexed single-cell profiling has enabled large-scale …

[HTML][HTML] Novel Klebsiella pneumoniae K23-Specific Bacteriophages From Different Families: Similarity of Depolymerases and Their Therapeutic Potential

…, DA Bespiatykh, VV Verevkin, EA Denisenko… - Frontiers in …, 2021 - frontiersin.org
Antibiotic resistance is a major public health concern in many countries worldwide. The rapid
spread of multidrug-resistant (MDR) bacteria is the main driving force for the development …

Toward bioactive yet antibacterial surfaces

…, IY Zhitnyak, NA Gloushankova, EA Denisenko… - Colloids and Surfaces B …, 2015 - Elsevier
… isolated Escherichia coli O78 (E. coli) and Neurospora crassa … TiCaPCON films are highly
efficient against E. coli bacteria and, … films was evaluated against clinically isolated E. coli O78 (…

Approaches for Controlled Ag+ Ion Release: Influence of Surface Topography, Roughness, and Bactericide Content

…, NV Shvindina, EA Denisenko… - … Applied Materials & …, 2017 - ACS Publications
… in physiological solution (<40 ppb), samples with specially fabricated surface reliefs (flakes
or holes) showed a pronounced antibacterial effect already after 3 h of immersion in E. coli …

[HTML][HTML] Characterization of the humanized FRG mouse model and development of an AAV-LK03 variant with improved liver lobular biodistribution

…, G Baltazar, E Zhu, M Jones, E Denisenko… - … Therapy Methods & …, 2023 - cell.com
Recent clinical successes have intensified interest in using adeno-associated virus (AAV)
vectors for therapeutic gene delivery. The liver is a key clinical target, given its critical …

Synergistic and long-lasting antibacterial effect of antibiotic-loaded TiCaPCON-Ag films against pathogenic bacteria and fungi

…, IY Zhitnyak, NA Gloushankova, EA Denisenko… - Materials Science and …, 2018 - Elsevier
… isolated Escherichia coli O78 (E. coli), Staphylococcus … a superb antibacterial activity
against E. coli bacteria. We … Gram-negative E. coli bacteria, Gram-positive S. aureus, and N. …