Atherosclerosis is a chronic inflammatory disease that arises from an imbalance in lipid
metabolism and a maladaptive immune response driven by the accumulation of cholesterol-…

During normal cellular activities, various processes inside of cells produce reactive oxygen
species (ROS). Some of the most common ROS are hydrogen peroxide (H 2 O 2 ), …

… In the current review, searches of the four databases retrieved 6881 records (see Electronic
searches). Our searches of other resources (reference and citation searches of included …

Background In women with breast cancer, the role of radical mastectomy, as compared with
less extensive surgery, has been a matter of debate. We report 25-year findings of a …

In this chapter we provide a brief history of ecological models as applied to health behavior
and describe ecological models as contemporary frameworks for integrating the theories and …

In 1976 we began a randomized trial to evaluate breast conservation by a segmental mastectomy
in the treatment of Stage I and II breast tumors ≤4 cm in size. The operation removes …

Background In 1976, we initiated a randomized trial to determine whether lumpectomy with
or without radiation therapy was as effective as total mastectomy for the treatment of invasive …

Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain
largely elusive. To identify genetic loci for obesity susceptibility, we examined associations …

Description of macrophage activation is currently contentious and confusing. Like the biblical
Tower of Babel, macrophage activation encompasses a panoply of descriptors used in …

Background The likelihood of distant recurrence in patients with breast cancer who have no
involved lymph nodes and estrogen-receptor–positive tumors is poorly defined by clinical …