User profiles for E. Kiermaier

Eva Kiermaier

Associate Professor for Immune & Tumor Biology
Verified email at uni-bonn.de
Cited by 724

N-linked glycosylation of folded proteins by the bacterial oligosaccharyltransferase

…, MF Feldman, BL Schulz, N Callewaert, E Kiermaier… - Science, 2006 - science.org
E. coli cells were labeled with 35 S-methionine for 15 s (A) or 30 s (B) and chased for the …
The ssTorA-AcrA fusion protein was expressed in E. coli cells harboring the pgl or pgl mut locus…

[HTML][HTML] Dynamic microtubule arrays in leukocytes and their role in cell migration and immune synapse formation

A Kopf, E Kiermaier - Frontiers in cell and developmental biology, 2021 - frontiersin.org
The organization of microtubule arrays in immune cells is critically important for a properly
operating immune system. Leukocytes are white blood cells of hematopoietic origin, which …

Polysialylation controls dendritic cell trafficking by regulating chemokine recognition

E Kiermaier, C Moussion, CT Veldkamp… - Science, 2016 - science.org
… S4, D and E). To substantiate that CCR7 is polysialylated in DCs, we used flow cytometry
to analyze cell-surface levels of polySia in Ccr7-deficient and control DCs and found reduced …

Microtubules control cellular shape and coherence in amoeboid migrating cells

…, D Trauner, H Häcker, KD Fischer, E Kiermaier… - Journal of Cell …, 2020 - rupress.org
… 1, c–e). We then quantified how far individual EB3 comets reached into the two protrusions
and found that upon junction point passage of the MTOC, comets in the loser protrusion …

Multiple centrosomes enhance migration and immune cell effector functions of mature dendritic cells

…, OJ Gruß, M Hons, S Wieser, E Kiermaier - Journal of Cell …, 2022 - rupress.org
… 3 e), the proportion of cells residing in G2 phase substantially declines, while red-emitting
and colorless cells accumulate (Fig. 4 e). Analysis of DNA content in immature and mature …

Solution structure of CCL19 and identification of overlapping CCR7 and PSGL-1 binding sites

CT Veldkamp, E Kiermaier, SJ Gabel-Eissens… - Biochemistry, 2015 - ACS Publications
… Most electronic Supporting Information files are available without a subscription to ACS Web
Editions. Such files may be downloaded by article for research use (if there is a public use …

[HTML][HTML] Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors

S Molatore, E Kiermaier, CB Jung, M Lee, E Pulz… - Molecular Cancer, 2010 - Springer
… (e) Live cell imaging of MCF7 cells transfected with p27wt or p27fs177 and treated for the
indicated times with CHX confirms the rapid degradation of p27fs177. Wt, wild-type; Untr, …

A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast

E Kiermaier, S Woehrer, Y Peng, K Mechtler… - Nature cell …, 2009 - nature.com
Kinetochores are large multiprotein complexes that mediate chromosome segregation in all
eukaryotes by dynamically connecting specialized chromosome regions, termed …

[HTML][HTML] A stable chemokine gradient controls directional persistence of migrating dendritic cells

…, D Guu, L Alvarez, C Küsters, E Kiermaier… - Frontiers in cell and …, 2022 - frontiersin.org
Navigation of dendritic cells (DCs) from the site of infection to lymphoid organs is guided by
concentration gradients of CCR7 ligands. How cells interpret chemokine gradients and how …

[HTML][HTML] Fetal liver macrophages contribute to the hematopoietic stem cell niche by controlling granulopoiesis

…, E Kiermaier, M Beyer, A Schlitzer, E Mass - Elife, 2024 - ncbi.nlm.nih.gov
… (A) Single-cell RNA-sequencing (scRNA-seq) analysis of wildtype CD11b low/+ cells isolated
from a fetal liver at developmental day (E)14.5. Clusters of possible macrophage subsets …