The immunosuppressive drug rapamycin has helped to identify a large signaling network
around the target of rapamycin (TOR) protein that integrates information on nutrient availability …

Bodily awareness is a central component of human sensation, action, and cognition. The
human body is subject to profound changes over the adult lifespan. We live in an aging society: …

The mTOR pathway is the central regulator of cell size 1 . External signals from growth factors
and nutrients converge on the mTORC1 multi-protein complex to modulate downstream …

The primary cilium has evolved as a multifunctional cellular compartment that decorates
most vertebrate cells. Cilia sense mechanical stimuli in various organs, but the molecular …

The deep dorsal horn is a poorly characterized spinal cord region implicated in processing
low-threshold mechanoreceptor (LTMR) information. We report an array of mouse genetic …

PTSD Coach is a mobile application (app) designed to help individuals who have post-traumatic
stress disorder (PTSD) symptoms better understand and self-manage their symptoms. It …

Mammalian target of rapamycin complex 1 (mTORC1) controls growth and survival in response
to metabolic cues. Oxidative stress affects mTORC1 via inhibitory and stimulatory inputs. …

Nephronophthisis is an autosomal recessive cystic kidney disease that leads to renal failure
in childhood or adolescence. Most NPHP gene products form molecular networks. Here we …

Tim-3 is a member of the TIM family of proteins (T-cell immunoglobulin mucin) involved in
the regulation of CD4+ T-cells. Tim-3 is a T H 1-specific type 1 membrane protein and …

… (E) Peak frame in the response to a 10 dot. (F) Response of all larvae (n = 9) to stimuli 0.5–…
(E) AF7 and AF9 responses to paramecia in nine larvae. Maximum ΔF/F is plotted for each trial…