Considerable evidence suggests that the formation of long-term memories requires a critical
period of new protein synthesis. Recently, the notion that some of these newly synthesized …

The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries
out diverse signaling tasks in both the central and peripheral nervous systems. Whereas …

▪ Abstract Studies over the past 20 years have revealed that gene expression in neurons is
carried out by a distributed network of translational machinery. One component of this …

… Kang and EM Schuman, data not shown. 11. The amplitude of the presynaptic fiber volley
did not change significantly after treatment with BDNF (20 ng/ml) (mean percent of baseline: …

Long-term potentiation (LTP) of synaptic transmission is a widely studied model of neuronal
plasticity. The induction of LTP is known to require processes in the postsynaptic neuron, …

… Miller and Amgen for supplying BDNF and NT-3, and Caltech faculty and the Schuman lab
for helpful discussions and comments. Supported by funds from the Sloan Foundation, John …

Circular RNAs (circRNAs) have re-emerged as an interesting RNA species. Using deep RNA
profiling in different mouse tissues, we observed that circRNAs were substantially enriched …

Many forms of long-lasting behavioral and synaptic plasticity require the synthesis of new
proteins. For example, long-term potentiation (LTP) that endures for more than an hour …

… Mayor, and all members of the Schuman laboratory for helpful discussions and comments; …
Mayor, and all members of the Schuman laboratory for helpful discussions and comments; …

… by the 5 and 3 dressed protein transport from the soma (Schuman, … lasting synaptic plasticity
(reviewed in Schuman, 1999a; … grateful to Gilles Laurent and members of the Schuman lab …