10.7554/eLife.19850.001 Actin has well established functions in cellular morphogenesis.
However, it is not well understood how the various actin assemblies in a cell are kept in a …

Background Monogenic diseases provide favorable opportunities to elucidate the molecular
mechanisms of disease progression and improve medical diagnostics. However, the …

Background In 2007, we published an opinion document to review the role of pegvisomant (PEG)
in the treatment of acromegaly. Since then, new evidence emerged on the biochemical …

Although the consumption of whole grain foods has been encouraged due to the association
between whole grains and health benefits, changes in the technological parameters and …

… Author links open overlay panel Marcos F Silva 1 , Michele EC Menis-Henrique 2 , Mária
HF Felisberto 2 3 , Rosana Goldbeck 1 , Maria TPS Clerici 2 … Bambu de corpo e alma …

Objectives The seroprevalence of antibodies against Cytomegalovirus (CMV) is an established
poor prognostic factor for patients receiving an allogeneic stem cell transplantation. …

Pituitary adenomas are common in the general population, and understanding their molecular
basis is of great interest. Combining chip-based technologies with genealogy data, we …

Context: AIP mutations (AIPmut) give rise to a pituitary adenoma predisposition that occurs
in familial isolated pituitary adenomas and less often in sporadic cases. The clinical and …

Context: Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are conditions at
high risk for the development of hypopituitarism. Objective: The objective of the study was to …

Context: Germline mutations in the MEN1 gene predispose to multiple endocrine neoplasia
type 1 (MEN1) syndrome, but in up to 20–25% of clinical MEN1 cases, no MEN1 mutations …