User profiles for E. Porta-Pardo
Eduard Porta-PardoJosep Carreras Leukaemia Research Institute Verified email at bsc.es Cited by 8677 |
[PDF][PDF] The immune landscape of cancer
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising
33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we …
33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we …
[PDF][PDF] Comprehensive characterization of cancer driver genes and mutations
Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced
algorithms to identify drivers now exist, but systematic attempts to combine and optimize them on …
algorithms to identify drivers now exist, but systematic attempts to combine and optimize them on …
[PDF][PDF] The functional impact of alternative splicing in cancer
… We also show the top 20 cases according to the number of MS samples for WES (E) and
WGS (F) data. For each gene and isoform (y axis), we show the number of patients for which we …
WGS (F) data. For each gene and isoform (y axis), we show the number of patients for which we …
[PDF][PDF] Perspective on oncogenic processes at the end of the beginning of cancer genomics
L Ding, MH Bailey, E Porta-Pardo, V Thorsson… - Cell, 2018 - cell.com
The Cancer Genome Atlas (TCGA) has catalyzed systematic characterization of diverse
genomic alterations underlying human cancers. At this historic junction marking the completion …
genomic alterations underlying human cancers. At this historic junction marking the completion …
[HTML][HTML] The immune landscape of cancer
(Immunity 48, 812–830.e1–e14; April 17, 2018) In the originally published version of this
article, the authors neglected to include Younes Mokrab and Aaron M. Newman as co-authors …
article, the authors neglected to include Younes Mokrab and Aaron M. Newman as co-authors …
[HTML][HTML] The structural coverage of the human proteome before and after AlphaFold
… We considered only hits with an e-value below 1e-8 and sequence identity ≥ 20%, the
limit thresholds for … We only kept those PFAM domains identified with an e-value below 1e-8. …
limit thresholds for … We only kept those PFAM domains identified with an e-value below 1e-8. …
[PDF][PDF] Pan-cancer proteogenomics connects oncogenic drivers to functional states
Cancer driver events refer to key genetic aberrations that drive oncogenesis; however, their
exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan-…
exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan-…
[HTML][HTML] A pan-cancer catalogue of cancer driver protein interaction interfaces
… Here we introduce an extended version of e-Driver that uses information on three-dimensional
structures of the mutated proteins to identify specific structural features. Then, the …
structures of the mutated proteins to identify specific structural features. Then, the …
Understanding oncogenicity of cancer driver genes and mutations in the cancer genomics era
Understanding oncogenicity of cancer driver genes and mutations in the cancer genomics
era - Porta‐Pardo - 2020 - FEBS Letters - Wiley Online Library … Eduard Porta-Pardo …
era - Porta‐Pardo - 2020 - FEBS Letters - Wiley Online Library … Eduard Porta-Pardo …
[PDF][PDF] Germline genetic contribution to the immune landscape of cancer
Understanding the contribution of the host's genetic background to cancer immunity may
lead to improved stratification for immunotherapy and to the identification of novel therapeutic …
lead to improved stratification for immunotherapy and to the identification of novel therapeutic …