BACKGROUND: The etiology of cardiovascular disease (CVD) is multifactorial. Efforts to
identify genes influencing CVD risk have met with limited success to date, likely because of the …

The role for a single dose of intravesical chemotherapy (IVC) after transurethral resection (TUR)
remains unclear in patients with non–muscle-invasive bladder cancer (NMIBC). Several …

… A higher-magnification image of the boxed area in d is shown in e. Black arrows indicate
representative inclusions in neurites (e–g), and arrowheads indicate cytoplasmic inclusions in …

To discuss the use of renal mass biopsy (RMB) for small renal masses (SRMs), formulate
technical aspects, outline potential pitfalls and provide recommendations for the practicing …

Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies
have identified common CKD susceptibility variants. The CKDGen consortium performed …

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using
whole-genome, exome and transcriptome sequencing of 2,754 childhood patients with ALL, we …

Dilated cardiomyopathy commonly causes heart failure and is the most frequent precipitating
cause of heart transplantation. Familial dilated cardiomyopathy has been shown to be …

Genome-wide association studies (GWAS) have identified 36 loci associated with body mass
index (BMI), predominantly in populations of European ancestry. We conducted a meta-…

Hypertension places a major burden on individual and public health, but the genetic basis
of this complex disorder is poorly understood. We conducted a genome-wide association …

Background CommonFTO(fat mass and obesity associated) gene variants have recently
been associated with body mass index (BMI) and obesity in several large studies. The role of …