User profiles for E. Taka
Elhan TakaIstanbul Technical University Verified email at itu.edu.tr Cited by 192 |
[HTML][HTML] Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age
A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
… astrocytes and microglia and apolipoprotein-E (ApoE) formation in brain slice culture [30]. …
dismutase (SOD), and the scavenging rate is much stronger than vitamins C and E [150]. …
dismutase (SOD), and the scavenging rate is much stronger than vitamins C and E [150]. …
[HTML][HTML] The anticancer effects of flavonoids through miRNAs modulations in triple-negative breast cancer
GM Adinew, E Taka, P Mendonca, SS Messeha… - Nutrients, 2021 - mdpi.com
… The flavonoid artonin E also has been found to induce apoptosis in a concentration and
time… Furthermore, this study showed that artonin E inhibits the expression of anti-apoptotic …
time… Furthermore, this study showed that artonin E inhibits the expression of anti-apoptotic …
[HTML][HTML] Therapeutic potential of thymoquinone in triple-negative breast cancer prevention and progression through the modulation of the tumor microenvironment
GM Adinew, E Taka, B Mochona, RB Badisa… - Nutrients, 2021 - mdpi.com
… It has also been reported that by targeting cyclin E, cyclin D1, and p27 proteins, TQ caused
cell cycle arrest, suppressing progression from G1 to S phase [41]. TQ can also induce …
cell cycle arrest, suppressing progression from G1 to S phase [41]. TQ can also induce …
Conformational transition of SARS-CoV-2 spike glycoprotein between its closed and open states
In 2020, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
infected millions of people worldwide and caused the coronavirus disease 2019 (COVID-19). …
infected millions of people worldwide and caused the coronavirus disease 2019 (COVID-19). …
Anti-inflammatory effects of thymoquinone in activated BV-2 microglial cells
E Taka, EA Mazzio, CB Goodman, N Redmon… - Journal of …, 2015 - Elsevier
Thymoquinone (TQ), the main pharmacological active ingredient within the black cumin
seed (Nigella sativa) is believed to be responsible for the therapeutic effects on chronic …
seed (Nigella sativa) is believed to be responsible for the therapeutic effects on chronic …
Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines and the gene expression NFκB …
MK Cobourne-Duval, E Taka, P Mendonca… - Journal of …, 2018 - Elsevier
Neuroinflammation and microglial activation are pathological markers of a number of central
nervous system (CNS) diseases. Chronic activation of microglia induces the release of …
nervous system (CNS) diseases. Chronic activation of microglia induces the release of …
Critical interactions between the SARS-CoV-2 spike glycoprotein and the human ACE2 receptor
… (e) Distribution of work applied during unbinding of RBD from PD for pulling velocities of
0.1 Å/ns (blue) and 2 Å/ns (coral). The thick line represents the average work values. (f) (Left) …
0.1 Å/ns (blue) and 2 Å/ns (coral). The thick line represents the average work values. (f) (Left) …
The antioxidant effects of thymoquinone in activated BV-2 murine microglial cells
MK Cobourne-Duval, E Taka, P Mendonca… - Neurochemical …, 2016 - Springer
Both neuroinflammation and microglial activation are pathological markers of a number of
central nervous system (CNS) diseases. During chronic activation of the microglial cells, the …
central nervous system (CNS) diseases. During chronic activation of the microglial cells, the …
[HTML][HTML] Molecular mechanisms of the anti-inflammatory effects of epigallocatechin 3-gallate (EGCG) in LPS-activated bv-2 microglia cells
A Payne, E Taka, GM Adinew, KFA Soliman - Brain Sciences, 2023 - mdpi.com
Chronic neuroinflammation is associated with many neurodegenerative diseases, such as
Alzheimer’s. Microglia are the brain’s primary immune cells, and when activated, they release …
Alzheimer’s. Microglia are the brain’s primary immune cells, and when activated, they release …
The role of apoptotic genes and protein-protein interactions in triple-negative breast cancer
GM Adinew, S Messeha, E Taka… - Cancer Genomics & …, 2023 - cgp.iiarjournals.org
Background/Aim: Compared to other breast cancer types, triple-negative breast cancer (TNBC)
has historically had few treatment alternatives. Therefore, exploring and pinpointing …
has historically had few treatment alternatives. Therefore, exploring and pinpointing …