Introduction: The frequency of CYP2D6 alleles, related to either a lack of or increased
enzymatic activity, which may lead to poor metabolism (PM) or ultrarapid metabolism (UM), can …

… Indeed, a demographic model elaborated by our group (Tarazona-Santos et al., 2001) revealed
a … Tarazona-Santos et al. (2001) suggested that cultural differences like farming and the …

While South Americans are underrepresented in human genomic diversity studies, Brazil
has been a classical model for population genetics studies on admixture. We present the …

The geographic structure of Y-chromosome variability has been analyzed in native
populations of South America, through use of the high-frequency Native American haplogroup …

We analyzed mtDNA sequence variation in 590 individuals from 18 south Amerindian
populations. The spatial pattern of mtDNA diversity in these populations fits well the model …

Native Americans from the Amazon, Andes, and coastal geographic regions of South America
have a rich cultural heritage but are genetically understudied, therefore leading to gaps in …

Brazil never had segregation laws defining membership of an ethnoracial group. Thus, the
composition of the Brazilian population is mixed and its ethnoracial classification is complex. …

As whole-genome sequencing (WGS) becomes the gold standard tool for studying
population genomics and medical applications, data on diverse non-European and admixed …

We present allele frequencies involving 39 pharmacogenetic biomarkers studied in Brazil,
and their distribution on self-reported race/color categories that: (1) involve a mix of …

Dementia is more prevalent in Blacks than in Whites, likely due to a combination of environmental
and biological factors. Paradoxically, clinical studies suggest an attenuation of APOE …