User profiles for E. Wamhoff
Eike-Christian WamhoffBioNTech SE Verified email at biontech.de Cited by 1105 |
Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex biophysical …
dynamic properties and nanoscale control. These nanostructures enable complex biophysical …
Programming structured DNA assemblies to probe biophysical processes
… electronic and vibrational states on energy-transfer efficiency remains a point of debate.
Electronic coherence occurs when electronic states … In contrast, electronic-vibrational coherence …
Electronic coherence occurs when electronic states … In contrast, electronic-vibrational coherence …
[HTML][HTML] Role of nanoscale antigen organization on B-cell activation probed using DNA origami
Vaccine efficacy can be increased by arraying immunogens in multivalent form on virus-like
nanoparticles to enhance B-cell activation. However, the effects of antigen copy number, …
nanoparticles to enhance B-cell activation. However, the effects of antigen copy number, …
Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosa
…, K Rox, A Varrot, D Hauck, EC Wamhoff… - Journal of the …, 2018 - ACS Publications
The opportunistic Gram-negative bacterium Pseudomonas aeruginosa is a leading pathogen
for infections of immuno-compromised patients and those suffering from cystic fibrosis. Its …
for infections of immuno-compromised patients and those suffering from cystic fibrosis. Its …
A specific, glycomimetic langerin ligand for human langerhans cell targeting
EC Wamhoff, J Schulze, L Bellmann… - ACS central …, 2019 - ACS Publications
… (e) 16 was docked into the carbohydrate binding site to rationalize the observations from 15
N HSQC and STD NMR experiments. The selected docking pose predicted the formation of π…
N HSQC and STD NMR experiments. The selected docking pose predicted the formation of π…
Controlling nuclease degradation of wireframe DNA origami with minor groove binders
Viruslike particles (VLPs) fabricated using wireframe DNA origami are emerging as promising
vaccine and gene therapeutic delivery platforms due to their programmable nature that …
vaccine and gene therapeutic delivery platforms due to their programmable nature that …
[HTML][HTML] Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
…, D Park, AB Kulesa, EC Wamhoff… - Nature …, 2019 - nature.com
… E: cluster of conventional excitatory synapses with the presence of most synaptic markers;
I: cluster of possible inhibitory synapses with the absence of most synaptic markers; S: cluster …
I: cluster of possible inhibitory synapses with the absence of most synaptic markers; S: cluster …
In Situ Covalent Functionalization of DNA Origami Virus-like Particles
… (E) AGE confirms structural integrity of nanostructures after functionalization and purification…
Most electronic Supporting Information files are available without a subscription to ACS Web …
Most electronic Supporting Information files are available without a subscription to ACS Web …
[HTML][HTML] Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds
EC Wamhoff, L Ronsard, J Feldman… - Nature …, 2024 - nature.com
… Briefly, SS320 E coli cells were transformed with the phI52 plasmid, based on the pUC19
vector, and the M13cp helper plasmid (generously provided by Andrew Bradbury, Los Alamos …
vector, and the M13cp helper plasmid (generously provided by Andrew Bradbury, Los Alamos …
[HTML][HTML] Bioproduction of pure, kilobase-scale single-stranded DNA
… Here, we optimize growth conditions using an E. coli helper strain combined with a miniphage
genome carrying only an f1 origin and a β-lactamase-encoding (bla) antibiotic resistance …
genome carrying only an f1 origin and a β-lactamase-encoding (bla) antibiotic resistance …