User profiles for E. de Nadal

EULALIA DE NADAL CLANCHET

Professor of Biochemistry and Molecular Biology, UPF - Affiliated Group Leader, IRB
Verified email at irbbarcelona.org
Cited by 6838

Controlling gene expression in response to stress

E De Nadal, G Ammerer, F Posas - Nature Reviews Genetics, 2011 - nature.com
Acute stress puts cells at risk, and rapid adaptation is crucial for maximizing cell survival.
Cellular adaptation mechanisms include modification of certain aspects of cell physiology, such …

[HTML][HTML] The p38 pathway: from biology to cancer therapy

…, M Joaquin, M Caballero, F Posas, E De Nadal - International journal of …, 2020 - mdpi.com
The p38 MAPK pathway is well known for its role in transducing stress signals from the
environment. Many key players and regulatory mechanisms of this signaling cascade have been …

[HTML][HTML] Dealing with osmostress through MAP kinase activation

E De Nadal, PM Alepuz, F Posas - EMBO reports, 2002 - embopress.org
de Nadal and F. Posas, unpublished results). Sko1 is an ATF/CREB factor whose …
components of the RNA pol II holoenzyme (E. de Nadal, PM Alepuz, M. Zapater, G. Ammerer and F. …

[HTML][HTML] The transcriptional response of yeast to saline stress

…, JA Heyman, JP Hoeffler, E De Nadal… - Journal of Biological …, 2000 - ASBMB
… Eulalia de Nadal Eulalia de Nadal … data generated from this work can be retrieved from the
Universidad Autonoma de Barcelona web site. Our results revealed that expression of a quite …

Distributed biological computation with multicellular engineered networks

…, J Kjellén, T Peeters, S Hohmann, E De Nadal… - Nature, 2011 - nature.com
… a, b, Cells can receive signals from other cells (IN) and external sources (E) (a) or just from
… d, e, The four basic functions implemented in our study are displayed. … Eulàlia de Nadal

The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes

E De Nadal, M Zapater, PM Alepuz, L Sumoy, G Mas… - Nature, 2004 - nature.com
… GST, GST–Rpd3, GST–Hda1 and His–Hog1 were expressed and purified from E. coli.
Hog1 was incubated with GST fusion proteins and was detected by immunoblotting using His …

[HTML][HTML] Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress

M Proft, A Pascual‐Ahuir, E De Nadal, J Ariño… - The EMBO …, 2001 - embopress.org
… To test whether the observed difference in GRE2 expression by SKO1(E), as compared with
… Accordingly we found that Sko1 (wild type) and Sko1(E) strongly and equally repressed the …

[HTML][HTML] Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II

PM Alepuz, E de Nadal, M Zapater, G Ammerer… - The EMBO …, 2003 - embopress.org
… ‡ PMAlepuz and E.de Nadal contributed equally to this work … The GST–Hog1 was purified
from E.coli and incubated with semipure RNA Pol II holoenzyme. The presence of Rpb1 was …

Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity

…, G Yaakov, E Garí, M Aldea, E De Nadal… - The EMBO …, 2006 - embopress.org
… The wild‐type Hsl1 and the Hsl1 S1220A mutant were expressed in E. coli and assayed
as in (C). Phosphorylated proteins were detected by autoradiography (P32) or Coomassie …

Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII–p38MAPK–pS249/T252RB pathway

…, PA Villalobos, II Wistuba, E de Nadal… - Cancer research, 2018 - AACR
Bone metastasis from prostate cancer can occur years after prostatectomy, due to reactivation
of dormant disseminated tumor cells (DTC) in the bone, yet the mechanism by which DTCs …