[HTML][HTML] In search of a cure: the development of therapeutics to alter the progression of spinal muscular atrophy
KS Ojala, EJ Reedich, CJ DiDonato, SD Meriney - Brain Sciences, 2021 - mdpi.com
Until the recent development of disease-modifying therapeutics, spinal muscular atrophy (SMA)
was considered a devastating neuromuscular disease with a poor prognosis for most …
was considered a devastating neuromuscular disease with a poor prognosis for most …
Spinal motoneurons respond aberrantly to serotonin in a rabbit model of cerebral palsy
EJ Reedich, LT Genry, PR Steele… - The Journal of …, 2023 - Wiley Online Library
… Reedich is a postdoctoral fellow at the George and Anne Ryan Institute for Neuroscience
at the University of Rhode Island. She is interested in changes to motor unit electrophysiology …
at the University of Rhode Island. She is interested in changes to motor unit electrophysiology …
Inhibitory interneurons show early dysfunction in a SOD1 mouse model of amyotrophic lateral sclerosis
…, PR Steele, LT Genry, EJ Reedich… - The Journal of …, 2023 - Wiley Online Library
Few studies in amyotrophic lateral sclerosis (ALS) measure effects of the disease on inhibitory
interneurons synapsing onto motoneurons (MNs). However, inhibitory interneurons could …
interneurons synapsing onto motoneurons (MNs). However, inhibitory interneurons could …
[HTML][HTML] Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn2B/− mouse model of spinal muscular atrophy
EJ Reedich, M Kalski, N Armijo, GA Cox… - Experimental …, 2021 - Elsevier
Spinal muscular atrophy (SMA) is a pediatric neuromuscular disease caused by genetic
deficiency of the survival motor neuron (SMN) protein. Pathological hallmarks of SMA are spinal …
deficiency of the survival motor neuron (SMN) protein. Pathological hallmarks of SMA are spinal …
[HTML][HTML] In vitro and in vivo effects of 2, 4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: context-specific modulation of SMN transcript levels
…, S Du, TL Foley, A Gopalsamy, EJ Reedich… - PLoS …, 2017 - journals.plos.org
C5-substituted 2,4-diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS
(DAQ-DcpSi) have been developed for the treatment of spinal muscular atrophy (SMA), …
(DAQ-DcpSi) have been developed for the treatment of spinal muscular atrophy (SMA), …
Hyperexcitability precedes motoneuron loss in the Smn2B/− mouse model of spinal muscular atrophy
KA Quinlan, EJ Reedich, WD Arnold… - Journal of …, 2019 - journals.physiology.org
… *KA Quinlan and EJ Reedich contributed equally to this work… *KA Quinlan and EJ Reedich
contributed equally to this work. … During this work, EJ Reedich was the Dr. Virginia Mullin …
contributed equally to this work. … During this work, EJ Reedich was the Dr. Virginia Mullin …
Enhanced nociceptive behavior and expansion of associated primary afferents in a rabbit model of cerebral palsy
EJ Reedich, LT Genry, MA Singer… - Journal of …, 2022 - Wiley Online Library
Spastic cerebral palsy (CP) is a movement disorder marked by hypertonia and hyperreflexia;
the most prevalent comorbidity is pain. Since spinal nociceptive afferents contribute to both …
the most prevalent comorbidity is pain. Since spinal nociceptive afferents contribute to both …
[PDF][PDF] Enhanced nociception in a rabbit model of cerebral palsy
EJ REEDICH, LT GENRY, CF CAVARSAN, EM AVILA… - academia.edu
The most prevalent comorbidity of cerebral palsy (CP) is pain. In order to investigate the
relationship between perinatal injuries that cause CP and nociception, we investigated …
relationship between perinatal injuries that cause CP and nociception, we investigated …
Neuromuscular System Degeneration in Mouse Models of Spinal Muscular Atrophy
EJ Reedich - 2020 - dl.acm.org
Neuromuscular function progressively deteriorates in spinal muscular atrophy (SMA), the
leading genetic cause of infant mortality. SMA is an autosomal recessive genetic disorder …
leading genetic cause of infant mortality. SMA is an autosomal recessive genetic disorder …
Direct evidence for both thermal and photochemical stepwise cleavage in a pair of isomeric azo compounds
DE Reedich, RS Sheridan - Journal of the American Chemical …, 1988 - ACS Publications
(9) Adam, W.; Dorr, MJ Am. Chem. Soc. 1987, 109, 1240. that previous efforts by others10
had failed to detect similar re-arrangement in thermolyses of 2. These results are particularly …
had failed to detect similar re-arrangement in thermolyses of 2. These results are particularly …