Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

…, JA Hartline, JK Parsons, JD Bearden, ED Crawford… - Jama, 2009 - jamanetwork.com
Context Secondary analyses of 2 randomized controlled trials and supportive epidemiologic
and preclinical data indicated the potential of selenium and vitamin E for preventing …

[HTML][HTML] Mortality results from a randomized prostate-cancer screening trial

GL Andriole, ED Crawford, RL Grubb III… - New England journal …, 2009 - Mass Medical Soc
Background The effect of screening with prostate-specific–antigen (PSA) testing and digital
rectal examination on the rate of death from prostate cancer is unknown. This is the first …

[HTML][HTML] Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer

…, EJ Small, D Raghavan, ED Crawford - … England Journal of …, 2004 - Mass Medical Soc
Background Mitoxantrone-based chemotherapy palliates pain without extending survival in
men with progressive androgen-independent prostate cancer. We compared docetaxel plus …

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

J Lamb, ED Crawford, D Peck, JW Modell, IC Blat… - science, 2006 - science.org
To pursue a systematic approach to the discovery of functional connections among diseases,
genetic perturbation, and drug action, we have created the first installment of a reference …

[HTML][HTML] Prevalence of prostate cancer among men with a prostate-specific antigen level≤ 4.0 ng per milliliter

…, LG Ford, SM Lippman, ED Crawford… - … England Journal of …, 2004 - Mass Medical Soc
Background The optimal upper limit of the normal range for prostate-specific antigen (PSA)
is unknown. We investigated the prevalence of prostate cancer among men in the Prostate …

[HTML][HTML] Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer

…, DP Wood Jr, D Raghavan, ED Crawford - … England Journal of …, 2003 - Mass Medical Soc
Background Despite aggressive local therapy, patients with locally advanced bladder
cancer are at significant risk for metastases. We evaluated the ability of neoadjuvant …

[HTML][HTML] The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia

…, LM Nyberg Jr, HS Clarke, ED Crawford… - … England Journal of …, 2003 - Mass Medical Soc
Background Benign prostatic hyperplasia is commonly treated with alpha-adrenergic–receptor
antagonists (alpha-blockers) or 5α-reductase inhibitors. The long-term effect of these …

[HTML][HTML] Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer

…, JR Caton Jr, N Munshi, ED Crawford - … England Journal of …, 2001 - Mass Medical Soc
Background The value of nephrectomy in metastatic renal-cell cancer has long been debated.
Several nonrandomized studies suggest a higher rate of response to systemic therapy …

A controlled trial of leuprolide with and without flutamide in prostatic carcinoma

ED Crawford, MA Eisenberger… - … England Journal of …, 1989 - Mass Medical Soc
To test the hypothesis that maximal androgen blockade improves the effectiveness of the
treatment of prostatic cancer, we conducted a randomized, double-blind trial in patients with …

[HTML][HTML] Darolutamide and survival in metastatic, hormone-sensitive prostate cancer

…, K Fizazi, CN Sternberg, ED Crawford… - … England Journal of …, 2022 - Mass Medical Soc
Background Darolutamide is a potent androgen-receptor inhibitor that has been associated
with increased overall survival among patients with nonmetastatic, castration-resistant …