The minimum infectious dose required to induce CWD infection in cervids remains unknown,
as does whether peripherally shed prions and/or multiple low dose exposures are …

The transmission of chronic wasting disease (CWD) has largely been attributed to contact
with infectious prions shed in excretions (saliva, urine, feces, blood) by direct animal-to-animal …

Chronic wasting disease (CWD) continues to spread or be recognized in the United States,
Canada, and Europe. CWD is diagnosed by demonstration of the causative misfolded prion …

The metazoan Hsp70 disaggregase protects neurons from proteotoxicity that arises from the
accumulation of misfolded protein aggregates. Hsp70 and its co-chaperones disassemble …

Infectivity associated with prion disease has been demonstrated in blood throughout the
course of disease, yet the ability to detect blood-borne prions by in vitro methods remains …

Chronic wasting disease is a fatal prion condition of cervids such as deer, elk, moose and
reindeer. Secretion and excretion of prion infectivity from North American cervids with this …

Bluetongue virus (BTV) is an economically important pathogen of ruminant species with
worldwide prevalence. While many BTV infections are asymptomatic, animals with symptomatic …

A 12-yr-old captive intact male maned wolf (Chrysocyon brachyurus) was diagnosed with a
fibrosarcoma of the incisive bones. The mass was excised by rostral maxillectomy, and the …

An infectious agent’s pathogenic and transmission potential is heavily influenced by early
events during the asymptomatic or subclinical phase of disease. During this phase, the …

Unit non-response is a well known but undesirable problem in sample surveys including the
National Compensation Survey (NCS) Program. In NCS, unit non-response occurs because …