User profiles for EJD Greenwood
Edward JD GreenwoodUniversity of Cambridge Verified email at cam.ac.uk Cited by 1452 |
Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway
… support, EJD Greenwood thanks the Wellcome Trust for an undergraduate summer
studentship, and KA Smith, JP Hewitson, Y. Harcus, and RM Maizels thank the Wellcome Trust for …
studentship, and KA Smith, JP Hewitson, Y. Harcus, and RM Maizels thank the Wellcome Trust for …
A prenylated dsRNA sensor protects against severe COVID-19
…, N Palmalux, DG Stewart, S Swingler, EJD Greenwood… - Science, 2021 - science.org
INTRODUCTION Interferons (IFNs) are cytokines that are rapidly deployed in response to
invading pathogens. By initiating a signaling cascade that stimulates the expression of …
invading pathogens. By initiating a signaling cascade that stimulates the expression of …
[HTML][HTML] No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor
The spike protein of SARS-CoV-2 is known to enable viral invasion into human cells through
direct binding to host receptors including ACE2. An alternate entry receptor for the virus …
direct binding to host receptors including ACE2. An alternate entry receptor for the virus …
SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies
…, P Sabberwal, JC Williamson, EJD Greenwood… - Elife, 2022 - elifesciences.org
The outcome of infection is dependent on the ability of viruses to manipulate the infected
cell to evade immunity, and the ability of the immune response to overcome this evasion. …
cell to evade immunity, and the ability of the immune response to overcome this evasion. …
Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants
EJD Greenwood, NJ Matheson, K Wals… - Elife, 2016 - elifesciences.org
10.7554/eLife.18296.001 Viruses manipulate host factors to enhance their replication and
evade cellular restriction. We used multiplex tandem mass tag (TMT)-based whole cell …
evade cellular restriction. We used multiplex tandem mass tag (TMT)-based whole cell …
[PDF][PDF] Promiscuous targeting of cellular proteins by Vpr drives systems-level proteomic remodeling in HIV-1 infection
EJD Greenwood, JC Williamson, A Sienkiewicz… - Cell reports, 2019 - cell.com
HIV-1 encodes four "accessory proteins" (Vif, Vpr, Vpu, and Nef), dispensable for viral
replication in vitro but essential for viral pathogenesis in vivo. Well characterized cellular targets …
replication in vitro but essential for viral pathogenesis in vivo. Well characterized cellular targets …
[HTML][HTML] A protease-activatable luminescent biosensor and reporter cell line for authentic SARS-CoV-2 infection
PP Gerber, LM Duncan, EJD Greenwood… - PLoS …, 2022 - journals.plos.org
Efforts to define serological correlates of protection against COVID-19 have been hampered
by the lack of a simple, scalable, standardised assay for SARS-CoV-2 infection and …
by the lack of a simple, scalable, standardised assay for SARS-CoV-2 infection and …
[PDF][PDF] The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
…, A Teixeira-Silva, A Naamati, EJD Greenwood… - Cell host & …, 2021 - cell.com
Silencing of nuclear DNA is an essential feature of innate immune responses to invading
pathogens. Early in infection, unintegrated lentiviral cDNA accumulates in the nucleus yet …
pathogens. Early in infection, unintegrated lentiviral cDNA accumulates in the nucleus yet …
Functional proteomic atlas of HIV infection in primary human CD4+ T cells
A Naamati, JC Williamson, EJD Greenwood, S Marelli… - Elife, 2019 - elifesciences.org
10.7554/eLife.41431.001 Viruses manipulate host cells to enhance their replication, and the
identification of cellular factors targeted by viruses has led to key insights into both viral …
identification of cellular factors targeted by viruses has led to key insights into both viral …
Human cytomegalovirus infection of epithelial cells increases SARS-CoV-2 superinfection by upregulating the ACE2 receptor
MR Perera, EJD Greenwood… - The Journal of …, 2023 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), has caused widespread morbidity and mortality since its …
coronavirus disease 2019 (COVID-19), has caused widespread morbidity and mortality since its …