User profiles for EL Pannkuk

Evan L Pannkuk

Georgetown University Medical Center
Verified email at georgetown.edu
Cited by 908

Metabolomic applications in radiation biodosimetry: exploring radiation effects through small molecules

EL Pannkuk, AJ Fornace Jr… - International journal of …, 2017 - Taylor & Francis
… of which were perturbed at 7 days post-exposure (Pannkuk et al. Citation2016a) in doses 2,
… Dr Pannkuk was supported by the training grant in the Tumor Biology Program 5T32CA9686…

A lipidomic and metabolomic serum signature from nonhuman primates exposed to ionizing radiation

EL Pannkuk, EC Laiakis, TD Mak, G Astarita, S Authier… - Metabolomics, 2016 - Springer
Introduction Due to dangers associated with potential accidents from nuclear energy and
terrorist threats, there is a need for high-throughput biodosimetry to rapidly assess individual …

Global metabolomic identification of long-term dose-dependent urinary biomarkers in nonhuman primates exposed to ionizing radiation

EL Pannkuk, EC Laiakis, S Authier… - Radiation …, 2015 - meridian.allenpress.com
Due to concerns surrounding potential large-scale radiological events, there is a need to
determine robust radiation signatures for the rapid identification of exposed individuals, which …

[HTML][HTML] Isolation and Identification of an Extracellular Subtilisin-Like Serine Protease Secreted by the Bat Pathogen Pseudogymnoascus destructans

EL Pannkuk, TS Risch, BJ Savary - PLoS One, 2015 - journals.plos.org
White nose syndrome (WNS) is a cutaneous fungal disease of bats. WNS is responsible for
unprecedented mortalities in North American cave bat populations. There have been few …

[HTML][HTML] Lipidomic signatures of nonhuman primates with radiation-induced hematopoietic syndrome

EL Pannkuk, EC Laiakis, VK Singh, AJ Fornace - Scientific reports, 2017 - nature.com
Concern over potential exposures of ionizing radiation (IR) to large populations has emphasized
the need for rapid and reliable methods of biodosimetry to determine absorbed dose …

[HTML][HTML] Alterations in cell motility, proliferation, and metabolism in novel models of acquired temozolomide resistant glioblastoma

DM Tiek, JD Rone, GT Graham, EL Pannkuk… - Scientific reports, 2018 - nature.com
Glioblastoma (GBM) is an aggressive and incurable tumor of the brain with limited treatment
options. Current first-line standard of care is the DNA alkylating agent temozolomide (TMZ), …

Disease recovery in bats affected by white-nose syndrome

NW Fuller, LP McGuire, EL Pannkuk… - Journal of …, 2020 - journals.biologists.com
Processes associated with recovery of survivors are understudied components of wildlife
infectious diseases. White-nose syndrome (WNS) in bats provides an opportunity to study …

Targeted metabolomics of nonhuman primate serum after exposure to ionizing radiation: Potential tools for high-throughput biodosimetry

EL Pannkuk, EC Laiakis, S Authier, K Wong… - RSC …, 2016 - pubs.rsc.org
There is a need for research to rapidly determine an individual's absorbed dose and its
potential health effects after a potential radiological or nuclear event that could expose large …

A metabolomic serum signature from nonhuman primates treated with a radiation countermeasure, gamma-tocotrienol, and exposed to ionizing radiation

EL Pannkuk, EC Laiakis, AJ Fornace Jr… - Health …, 2018 - journals.lww.com
The search for and development of radiation countermeasures to treat acute lethal radiation
injury has been underway for the past six decades, resulting in the identification of multiple …

Gas chromatography/mass spectrometry metabolomics of urine and serum from nonhuman primates exposed to ionizing radiation: Impacts on the tricarboxylic acid …

EL Pannkuk, EC Laiakis, S Authier… - Journal of proteome …, 2017 - ACS Publications
Ionizing radiation (IR) directly damages cells and tissues or indirectly damages them through
reactive free radicals that may lead to longer term adverse sequelae such as cancers, …