[HTML][HTML] Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine

…, P Brankin, M McNeil, C Low, D Mallinson, EM Gourlay… - Plos one, 2019 - journals.plos.org
Here we describe a collaboration between industry, the National Health Service (NHS) and
academia that sought to demonstrate how early understanding of both pharmacology and …

Strategies for human genome modification using engineered nucleases and transcription factors

EM Gourlay - 2015 - theses.gla.ac.uk
VEZF1 is a highly conserved vertebrate transcription factor that is essential for mammalian
development. The gene regulatory functions of VEZF1 are largely undetermined. The …

[HTML][HTML] Bovine mitochondrial peroxiredoxin III forms a two-ring catenane

Z Cao, AW Roszak, LJ Gourlay, JG Lindsay, NW Isaacs - Structure, 2005 - cell.com
… Preliminary data from analytical ultracentrifugation (AUC) and EM studies indicate that the
SP-22 C168S preparations employed for crystallization contain a mixed population of single- …

Substrate factors that influence the synergistic interaction of AA9 and cellulases during the enzymatic hydrolysis of biomass

J Hu, V Arantes, A Pribowo, K Gourlay… - Energy & Environmental …, 2014 - pubs.rsc.org
… Interestingly, a strong correlation was evident between the CBM2a [thin space (1/6-em)] : [thin
space (1/6-em)] CBM44 adsorption ratio and the extent of AA9 boosting effect on the …

[PDF][PDF] Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine

…, P Brankin, M McNeil, C Low, D Mallinson, EM Gourlay… - 2019 - discovery.dundee.ac.uk
Here we describe a collaboration between industry, the National Health Service (NHS) and
academia that sought to demonstrate how early understanding of both pharmacology and …

Efficacy of a Bruton's Tyrosine Kinase Inhibitor (PRN‐473) in the treatment of canine pemphigus foliaceus

…, M Masjedizadeh, P Nunn, SG Gourlay… - Veterinary …, 2020 - Wiley Online Library
… O título de IgG anti-DSC-1 diminuiu em três cães, aumentou em dois, não foi detectado em
três e não foi realizado no cão retirado. … Possíveis efeitos adversos ocorreram em três cães. …

Open trial of Bruton's tyrosine kinase inhibitor (PRN1008) in the treatment of canine pemphigus foliaceus

…, M Masjedizadeh, P Nunn, SG Gourlay… - Veterinary …, 2020 - Wiley Online Library
… Três cães continuaram a melhorar e mantiveram a remissão quase completa em 20 … 1
diminuiu drasticamente em um cão, foi indetectável em dois e não foi interpretável em um …

Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics

DT Warren, PD Andrews, CW Gourlay… - Journal of cell …, 2002 - journals.biologists.com
Sla1p is a protein required for cortical actin patch structure and organisation in budding
yeast. Here we use a combination of immunofluorescence microscopy and biochemical …

Threshold practices: Becoming a student through academic literacies

L Gourlay - London review of education, 2009 - journals.uclpress.co.uk
Student transitions into the university are often conceived of via an apprentice-type model,
or as entrance into a'community of practice'. This paper disputes the applicability of these …

Directions and indirect action: Learner adaptation of a classroom task

L Gourlay - ELT Journal, 2005 - academic.oup.com
… It was em boring and you got tired to repeat, if we were … groups of people is better and also
em . . . you have the other … em certainly it was more natural and spontaneous to em to form …