Long bone formation is a complex process that requires precise transcriptional control of
gene expression programs in mesenchymal progenitor cells. Histone deacetylases (Hdacs) …

Long bones are formed and repaired through the process of endochondral ossification.
Activation of G protein-coupled receptor (GPCR) signaling pathways is crucial for skeletal …

Endochondral ossification is tightly controlled by a coordinated network of signaling cascades
including parathyroid hormone (PTH). Pleckstrin homology (PH) domain and leucine rich …

A system is described for performing multicolor fluorescence image cytometry of cell preparations.
After the setting up stage, the operation is automatic: the microscope fields are found …

Objective The purpose of this study was to investigate the effect of age and oxidative stress
on regulation of nuclear factor erythroid-2-related factor 2 (Nrf2) in young, old, and …

Primary bone tumors are rare cancers that cause significant morbidity and mortality. The
recent identification of recurrent mutations in histone genes H3F3A and H3F3B within specific …

In Multi-Parameter Fluorescence microscopy (MPF), as many as five fluorophores have
been used simultaneously, to study structural and physiological properties of cells in culturel. …

We, representing the Society for Pediatric Pathology (SPP), commend Dr Sinard and members
of the Autopsy Committee of the College of American Pathologists (CAP) for writing the …

Since the embedding of the principles of the 3Rs (Replacement, Reduction and Refinement)
in national and international regulations on the use of animals, scientists have been …

… IA With F-Actin The labeling of polymerized actin was achieved by a modification of the method
of Wang and Taylor (29). Monomeric G-… DL Taylor on this project is greatly appreciated. …