A true understanding of genetic and metabolic function and design is facilitated by
mathematical and computational methods for analyzing biochemical systems. This hands-on …

The organization, regulation and dynamical responses of biological systems are in many
cases too complex to allow intuitive predictions and require the support of mathematical …

An enormous variety of nonlinear differential equations and functions have been recast
exactly in the canonical form called an S-system. This is a system of nonlinear ordinary …

Rationale: Modern molecular biology is generating data of unprecedented quantity and
quality. Particularly exciting for biochemical pathway modeling and proteomics are …

High levels of polychlorinated biphenyls (PCBs) have been reported in the tissues of some
species of marine mammals. The high concentrations are of concern because a growing …

This year we celebrate the 150th anniversary of the law of mass action. This law is often
assumed to have been “there” forever, but it has its own history, background, and a definite …

Facility in the targeted manipulation of the genetic and metabolic composition of organisms,
combined with unprecedented computational power, is forging a niche for a new …

Biochemical systems theory (BST) is the foundation for a set of analytical andmodeling tools
that facilitate the analysis of dynamic biological systems. This paper depicts major …

Inflammation is a normal, robust physiological process. It can also be viewed as a complex
system that senses and attempts to resolve homeostatic perturbations initiated from within the …

The complexity of morphogenesis poses a fundamental challenge to understanding the
mechanisms governing the formation of biological patterns and structures. Over the past century, …