Histone variant H2A.Z-containing nucleosomes are incorporated at most eukaryotic promoters.
This incorporation is mediated by the conserved SWR1 complex, which replaces histone …

The histone variant H2A.Z is a genome-wide signature of nucleosomes proximal to
eukaryotic regulatory DNA. Whereas the multisubunit chromatin remodeler SWR1 is known to …

The histone variant H2AZ marks nucleosomes flanking the promoters of most genes of
budding yeast. The incorporation of H2AZ into chromatin is dependent on the SWR1 complex, …

The histone variant H2AZ is incorporated preferentially at specific locations in chromatin to
modulate chromosome functions. In Saccharomyces cerevisiae, deposition of histone H2AZ …

Copper serves as the essential cofactor for a number of enzymes involved in redox chemistry
and virtually all organisms must accumulate trace levels of copper in order to survive. …

Variant histone H2AZ-containing nucleosomes are involved in the regulation of gene
expression. In Saccharomyces cerevisiae, chromatin deposition of histone H2AZ is mediated by …

10.7554/eLife.14243.001 The assembly of the preinitiation complex (PIC) occurs upstream
of the +1 nucleosome which, in yeast, obstructs the transcription start site and is frequently …

The NMR structure of budding yeast chaperone Chz1 complexed with histones H2A.Z-H2B
has been determined. Chz1 forms a long irregular chain capped by two short α-helices, and …

Manganese-containing superoxide dismutase (SOD2) plays a critical role in guarding against
mitochondrial oxidative stress and is essential for survival of many organisms. Despite the …

Manganese-dependent superoxide dismutase 2 (SOD2) in the mitochondria plays a key
role in protection against oxidative stress. Here we probed the pathway by which SOD2 …