Differences in immune responses to viruses and autoimmune diseases such as systemic
lupus erythematosus (SLE) can show sexual dimorphism. Age-associated B cells (ABC) are a …

Effective immune responses require the precise regulation of dynamic interactions between
hematopoietic and non-hematopoietic cells. The Rho subfamily of GTPases, which includes …

Germinal center (GC) responses require B cells to respond to a dynamic set of intercellular
and microenvironmental signals that instruct B cell positioning, differentiation, and metabolic …

Age-associated B cells (ABCs) are a subset of B cells dependent on the transcription factor T-bet
that accumulate prematurely in autoimmune settings. The pathways that regulate ABCs …

Post-transcriptional modifications can control protein abundance, but the extent to which
these alterations contribute to the expression of T helper (T H ) lineage-defining factors is …

Background Detailed molecular analyses of cells from rheumatoid arthritis (RA) synovium
hold promise in identifying cellular phenotypes that drive tissue pathology and joint damage. …

… Anca Askanase formed the idea for the article; Wei Tang, Leila Khalili, and Edd Ricker
performed the literature search; Wei Tang performed the data analysis; Leila Khalili, Yevgeniya …

Activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL) is an aggressive subtype
of lymphoma usually associated with inferior outcomes. ABC-DLBCL exhibits plasmablastic …

Extranodal lymphomas feature a very poor prognosis. The identification of phenotypically
distinguishable prospective precursor cells represents a milestone in the pursuit of earlier …

The Rho kinases, or ROCKs, are a family of serine-threonine kinases that serve as key
downstream effectors for Rho GTPases. The ROCKs are increasingly recognized as critical …