Acetylcholinesterase (AChE) enzymatic inhibition is an important target for the management
of Alzheimer disease (AD) and AChE inhibitors are the mainstay drugs for its treatment. In …

Introduction Enzymatic inhibition of acetylcholinesterase (AChE) is an essential therapeutic
target for the treatment of Alzheimer's disease (AD) and AChE inhibitors are the first‐line …

Amaryllidaceae plants are the commercial source of galanthamine, an alkaloid approved for
the clinical treatment of Alzheimer’s disease. The chemistry and bioactivity of Chilean …

Cancer is a major cause of death and an impediment to increasing life expectancy worldwide.
With the aim of finding new molecules for chemotherapeutic treatment of epidemiological …

Zephyranthes carinata Herb., a specie of the Amaryllidoideae subfamily, has been reported
to have inhibitory activity against acetylcholinesterase. However, scientific evidence related …

Aims Determine a relationship between the neuroprotective activity and the antioxidant
capacity of the Amaryllidaceae alkaloids in a model of Glu excitotoxicity in rat cortical neurons. …

The Amaryllidaceae family has proven to be a rich source of active compounds, which are
characterized by unique skeleton arrangements and a broad spectrum of biological activities. …

Plant biodiversity is an important source of compounds with medicinal properties. The alkaloid
galanthamine, first isolated from Galanthus woronowii (Amaryllidaceae), is approved by …

It is estimated that 50 million people in the world live with dementia, 60–70% of whom suffer
from Alzheimer’s disease (AD). Different factors are involved in the development of AD, …

The application of antiaging agents can contribute to the prevention and control of skin
photoaging. In the current research, nine quinoline–hydrazone hybrids were synthesized to …