User profiles for Edoardo Micotti
 | Edoardo MicottiDept. of Neuroscience - Mario Negri Institute for Pharmacological Research Verified email at marionegri.it Cited by 2567 |
CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents
…, G Chece, C Lauro, A Paladini, E Micotti… - Journal of …, 2011 - Soc Neuroscience
The chemokine CX3CL1 and its receptor CX3CR1 are constitutively expressed in the nervous
system. In this study, we used in vivo murine models of permanent middle cerebral artery …
system. In this study, we used in vivo murine models of permanent middle cerebral artery …
One-pot synthesis and characterization of size-controlled bimagnetic FePt− Iron oxide heterodimer nanocrystals
A one-pot, two-step colloidal strategy to prepare bimagnetic hybrid nanocrystals (HNCs),
comprising size-tuned fcc FePt and inverse spinel cubic iron oxide domains epitaxially …
comprising size-tuned fcc FePt and inverse spinel cubic iron oxide domains epitaxially …
Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia
…, S Fumagalli, R Ottria, JJ Reina, A Paladini, E Micotti… - Circulation, 2012 - Am Heart Assoc
Background— The involvement of the complement system in brain injury has been scarcely
investigated. Here, we document the pivotal role of mannose-binding lectin (MBL), one of …
investigated. Here, we document the pivotal role of mannose-binding lectin (MBL), one of …
Single severe traumatic brain injury produces progressive pathology with ongoing contralateral white matter damage one year after injury
There is increasing recognition that traumatic brain injury (TBI) may initiate long-term
neurodegenerative processes, particularly chronic traumatic encephalopathy. However, insight into …
neurodegenerative processes, particularly chronic traumatic encephalopathy. However, insight into …
Paclitaxel enhances therapeutic efficacy of the F8-IL2 immunocytokine to EDA-fibronectin–positive metastatic human melanoma xenografts
The selective delivery of bioactive agents to tumors reduces toxicity and enhances the
efficacy of anticancer therapies. In this study, we show that the antibody F8, which recognizes …
efficacy of anticancer therapies. In this study, we show that the antibody F8, which recognizes …
Multiple drug delivery hydrogel system for spinal cord injury repair strategies
The multifactorial pathological progress of spinal cord injury (SCI) is probably the main
reason behind the absence of efficient therapeutic approaches. Hence, very recent highlights …
reason behind the absence of efficient therapeutic approaches. Hence, very recent highlights …
[PDF][PDF] Bovine serum albumin‐based magnetic nanocarrier for MRI diagnosis and hyperthermic therapy: a potential theranostic approach against cancer
…, A Lascialfari, M Corti, P Marmorato, J Ponti, E Micotti… - small, 2010 - academia.edu
After the 2005 milestone in clinical application of paclitaxel–albumin nanoparticles (NPs) for
the treatment of metastatic breast cancer,[1] albumin NPs have been thoroughly …
the treatment of metastatic breast cancer,[1] albumin NPs have been thoroughly …
In vivo imaging of glia activation using 1H‐magnetic resonance spectroscopy to detect putative biomarkers of tissue epileptogenicity
M Filibian, A Frasca, D Maggioni, E Micotti… - …, 2012 - Wiley Online Library
Purpose: Long‐lasting activation of glia occurs in brain during epileptogenesis, which
develops after various central nervous system (CNS) injuries. Glia is the cell source of the …
develops after various central nervous system (CNS) injuries. Glia is the cell source of the …
[HTML][HTML] Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease
…, A Paladini, C Balducci, E Micotti… - PLoS …, 2015 - journals.plos.org
Fatal familial insomnia (FFI) and a genetic form of Creutzfeldt-Jakob disease (CJD 178 ) are
clinically different prion disorders linked to the D178N prion protein (PrP) mutation. The …
clinically different prion disorders linked to the D178N prion protein (PrP) mutation. The …
Bevacizumab-induced inhibition of angiogenesis promotes a more homogeneous intratumoral distribution of paclitaxel, improving the antitumor response
…, R Frapolli, P Richter, A Decio, O Dirsch, E Micotti… - Molecular cancer …, 2016 - AACR
The antitumor activity of angiogenesis inhibitors is reinforced in combination with chemotherapy.
It is debated whether this potentiation is related to a better drug delivery to the tumor …
It is debated whether this potentiation is related to a better drug delivery to the tumor …