User profiles for Eduardo Gallardo Toledo
Eduardo Gallardo-ToledoUniversity of Liverpool Verified email at liverpool.ac.uk Cited by 335 |
Peptides and proteins used to enhance gold nanoparticle delivery to the brain: preclinical approaches
…, F Morales, E Gallardo-Toledo… - International journal …, 2015 - Taylor & Francis
An exciting and emerging field in nanomedicine involves the use of gold nanoparticles (AuNPs)
in the preclinical development of new strategies for the treatment and diagnosis of brain-…
in the preclinical development of new strategies for the treatment and diagnosis of brain-…
The influence of size and chemical composition of silver and gold nanoparticles on in vivo toxicity with potential applications to central nervous system diseases
DF Báez, E Gallardo-Toledo, MP Oyarzún… - International journal …, 2021 - Taylor & Francis
The physicochemical and optical properties of silver nanoparticles (SNPs) and gold
nanoparticles (GNPs) have allowed them to be employed for various biomedical applications, …
nanoparticles (GNPs) have allowed them to be employed for various biomedical applications, …
Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2
…, E Salas-Huenuleo, E Gallardo-Toledo… - …, 2017 - Future Medicine
Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system
of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can …
of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can …
Intranasal administration of gold nanoparticles designed to target the central nervous system: fabrication and comparison between nanospheres and nanoprisms
The presence of the blood–brain barrier (BBB) limit gold nanoparticles (GNP) accumulation
in central nervous system (CNS) after intravenous (IV) administration. The intranasal (IN) …
in central nervous system (CNS) after intravenous (IV) administration. The intranasal (IN) …
Transfersomes as alternative topical nanodosage forms for the treatment of skin disorders
P Oyarzún, E Gallardo-Toledo, J Morales… - Nanomedicine, 2021 - Future Medicine
Topical drug delivery is a promising approach to treat different skin disorders. However, it
remains a challenge mainly due to the nature and rigidity of the nanosystems, which limit deep …
remains a challenge mainly due to the nature and rigidity of the nanosystems, which limit deep …
[HTML][HTML] Evaluation of Nafamostat as chemoprophylaxis for SARS-CoV-2 infection in hamsters
M Neary, J Sharp, E Gallardo-Toledo, J Herriott, E Kijak… - Viruses, 2023 - mdpi.com
The successful development of a chemoprophylaxis against SARS-CoV-2 could provide a
tool for infection prevention that is implementable alongside vaccination programmes. …
tool for infection prevention that is implementable alongside vaccination programmes. …
Functionalization with PEG/Angiopep-2 peptide to improve the delivery of gold nanoprisms to central nervous system: In vitro and in vivo studies
A Tapia-Arellano, E Gallardo-Toledo, C Ortiz… - Materials Science and …, 2021 - Elsevier
One of main drawbacks for the treatment of neurodegenerative pathologies is ensuring the
delivery of therapeutic agents into the central nervous system (CNS). Nowadays, gold …
delivery of therapeutic agents into the central nervous system (CNS). Nowadays, gold …
The curvature of gold nanoparticles influences the exposure of amyloid-β and modulates its aggregation process
Gold nanoparticles (GNP) are tunable nanomaterials that can be used to develop rational
therapeutic inhibitors against the formation of pathological aggregates of proteins. In the case …
therapeutic inhibitors against the formation of pathological aggregates of proteins. In the case …
[HTML][HTML] β-cyclodextrin-based nanosponges inclusion compounds associated with gold nanorods for potential NIR-II drug delivery
…, E Cortés-Adasme, E Gallardo-Toledo… - Pharmaceutics, 2022 - mdpi.com
This article describes the synthesis and characterization of two nanocarriers consisting of β-cyclodextrin-based
nanosponges (NSs) inclusion compounds (ICs) and gold nanorods (…
nanosponges (NSs) inclusion compounds (ICs) and gold nanorods (…
[HTML][HTML] Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters
E Gallardo-Toledo, M Neary, J Sharp, J Herriott, E Kijak… - Viruses, 2023 - mdpi.com
Pibrentasvir (PIB) has been demonstrated to block exonuclease activity of the SARS-CoV-2
polymerase, protecting favipiravir (FVP) and remdesivir (RDV) from post-incorporation …
polymerase, protecting favipiravir (FVP) and remdesivir (RDV) from post-incorporation …