User profiles for Eduardo R. Cobo
Eduardo R. CoboUniversity of Calgary Verified email at ucalgary.ca Cited by 2198 |
A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target
…, D Parsonage, RM Andrade, C He, ER Cobo… - Nature medicine, 2012 - nature.com
Entamoeba histolytica, a protozoan intestinal parasite, is the causative agent of human
amebiasis. Amebiasis is the fourth leading cause of death and the third leading cause of …
amebiasis. Amebiasis is the fourth leading cause of death and the third leading cause of …
A review of sexually transmitted bovine trichomoniasis and campylobacteriosis affecting cattle reproductive health
The objective is to discuss sexually transmitted diseases caused by Tritrichomonas foetus (T
foetus) and Campylobacter fetus (C fetus) subsp. venerealis, with a focus on prevalence, …
foetus) and Campylobacter fetus (C fetus) subsp. venerealis, with a focus on prevalence, …
[HTML][HTML] Antimicrobial human β-defensins in the colon and their role in infectious and non-infectious diseases
ER Cobo, K Chadee - Pathogens, 2013 - mdpi.com
β-defensins are small cationic antimicrobial peptides secreted by diverse cell types including
colonic epithelial cells. Human β-defensins form an essential component of the intestinal …
colonic epithelial cells. Human β-defensins form an essential component of the intestinal …
MUC2 mucin and butyrate contribute to the synthesis of the antimicrobial peptide cathelicidin in response to Entamoeba histolytica-and dextran sodium sulfate …
ER Cobo, V Kissoon-Singh, F Moreau… - Infection and …, 2017 - Am Soc Microbiol
Embedded in the colonic mucus are cathelicidins, small cationic peptides secreted by colonic
epithelial cells. Humans and mice have one cathelicidin-related antimicrobial peptide (…
epithelial cells. Humans and mice have one cathelicidin-related antimicrobial peptide (…
[HTML][HTML] Host innate immune responses and microbiome profile of neonatal calves challenged with Cryptosporidium parvum and the effect of bovine colostrum …
Calves are highly susceptible to gastrointestinal infection with Cryptosporidium parvum (C.
parvum), which can result in watery diarrhea and eventually death or impaired development. …
parvum), which can result in watery diarrhea and eventually death or impaired development. …
Host defense cathelicidins in cattle: types, production, bioactive functions and potential therapeutic and diagnostic applications
…, PA Cavalcante, HW Barkema, ER Cobo - International journal of …, 2018 - Elsevier
Cathelicidins are a primitive class of host defense peptides and are known for their broad–spectrum
antimicrobial activity against bacteria, fungi, and enveloped viruses. These small, …
antimicrobial activity against bacteria, fungi, and enveloped viruses. These small, …
[HTML][HTML] Molecular epidemiology and distribution of antimicrobial resistance genes of Staphylococcus species isolated from Chinese dairy cows with clinical mastitis
Staphylococcus species, categorized into Staphylococcus aureus and non-aureus
staphylococci (NAS), are frequent causes of mastitis in dairy cattle around the world. Current …
staphylococci (NAS), are frequent causes of mastitis in dairy cattle around the world. Current …
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
…, DY Cheung, R Lozano, ER Cobo… - Proceedings of the …, 2013 - National Acad Sciences
Metronidazole and other 5-nitroimidazoles (5-NI) are among the most effective antimicrobials
available against many important anaerobic pathogens, but evolving resistance is …
available against many important anaerobic pathogens, but evolving resistance is …
[HTML][HTML] The network of colonic host defense peptides as an innate immune defense against enteropathogenic bacteria
Host defense peptides, abundantly secreted by colonic epithelial cells and leukocytes, are
proposed to be critical components of an innate immune response in the colon against …
proposed to be critical components of an innate immune response in the colon against …
[HTML][HTML] Klebsiella pneumoniae isolated from bovine mastitis is cytopathogenic for bovine mammary epithelial cells
Klebsiella pneumoniae, a common cause of clinical mastitis (CM) in dairy cows, can cause
severe clinical symptoms. However, its pathogenicity in the bovine mammary gland is not …
severe clinical symptoms. However, its pathogenicity in the bovine mammary gland is not …