X-linked lissencephaly and "double cortex" are allelic human disorders mapping to Xq22.3-Xq23
associated with arrest of migrating cerebral cortical neurons. We identified a novel 10 …

KCNQ (K V 7) potassium channels underlie subthreshold M-currents that stabilize the
neuronal resting potential and prevent repetitive firing of action potentials. Here, antibodies …

Mutations in the gene encoding the K + channel KCNQ2 cause neonatal epilepsy and
myokymia, indicating that KCNQ2 regulates the excitability of CNS neurons and motor axons, …

A double-blind placebo trial was conducted to determine the effect of moderate to high loads
of Trichuris trichiura (whipworm) infection on the cognitive functions of 159 school children (…

Mutations in the potassium channel subunit KCNQ2 lead to benign familial neonatal
convulsions, a dominantly inherited form of generalized epilepsy. In heterologous cells, KCNQ2 …

Members of the Kv7 family (Kv7.2–Kv7.5) generate a subthreshold K + current, the M− current.
This regulates the excitability of many peripheral and central neurons. Recent evidence …

Acetylcholine excites many central and autonomic neurons through inhibition of M-channels,
slowly activating, noninactivating voltage-gated potassium channels. We here provide …

… 4th ed … Cooper and Joan E. Steinman, Mary Kay Kane -- v. 14: Charles Alan Wright,
Arthur R. … Cooper and Helen Hershkoff …

Objective: To advance the understanding of KCNQ2 encephalopathy genotype–phenotype
relationships and to begin to assess the potential of selective KCNQ channel openers as …

GABA B receptors are heterodimeric G protein-coupled receptors composed of R1 and R2
subunits that mediate slow synaptic inhibition in the brain by activating inwardly rectifying K + …