Identifying new targeted therapies that kill tumor cells while sparing normal tissue is a major
challenge of cancer research. Using a high-throughput chemical synthetic lethal screen, we …

Most current imaging systems developed for tomographic investigations of intact tissues
using diffuse photons suffer from a limited number of sources and detectors. In this paper we …

Magnetic resonance imaging (MRI) allows noninvasive and three-dimensional visualization
of whole organisms over time, and, therefore, would be ideally suited to monitor cell …

… Taken together with the results of the study by Graves, et al.,8 these results demonstrate
that, on average, one third to one half of the nonenhancing regions of malignant glioma contain …

Purpose: Functional/metabolic information provided by MR-spectroscopy (MRSI) suggests
MRI may not be a reliable indicator of active and microscopic disease in malignant brain …

Radiation therapy is a mainstay of cancer treatment but does not always lead to complete
tumor regression. Here we combine radiotherapy with blockade of the ‘don’t-eat-me’ cell-…

Aim To evaluate the impact of ultra-rapid FLASH mouse whole brain irradiation on hippocampal
dendritic spines and neuroinflammation, factors associated with cognitive impairment …

PURPOSE: To evaluate the prognostic value of metabolic tumor volume measured on 18F-fluorodeoxyglucose
positron emission tomography (FDG-PET) imaging and other clinical …

PURPOSE: In lung cancer, stage is an important prognostic factor for disease progression
and survival. However, stage may be simply a surrogate for underlying tumor burden. Our …

2′3′-Cyclic GMP-AMP (cGAMP) is an intracellular second messenger that is synthesized
in response to cytosolic double-stranded DNA and activates the innate immune STING …