DeepCell Kiosk: scaling deep learning–enabled cellular image analysis with Kubernetes
…, N Greenwald, V Vijayakumar, B Chang, E Pao… - Nature …, 2021 - nature.com
Deep learning is transforming the analysis of biological images, but applying these models
to large datasets remains challenging. Here we describe the DeepCell Kiosk, cloud-native …
to large datasets remains challenging. Here we describe the DeepCell Kiosk, cloud-native …
[HTML][HTML] Label-free isolation of prostate circulating tumor cells using Vortex microfluidic technology
There has been increased interest in utilizing non-invasive “liquid biopsies” to identify
biomarkers for cancer prognosis and monitoring, and to isolate genetic material that can predict …
biomarkers for cancer prognosis and monitoring, and to isolate genetic material that can predict …
Accurate cell tracking and lineage construction in live-cell imaging experiments with deep learning
…, D Kyme, C Pavelchek, T Price, T Kudo, E Pao… - Biorxiv, 2019 - biorxiv.org
Live-cell imaging experiments have opened an exciting window into the behavior of living
systems. While these experiments can produce rich data, the computational analysis of these …
systems. While these experiments can produce rich data, the computational analysis of these …
[HTML][HTML] Label-free enumeration, collection and downstream cytological and cytogenetic analysis of circulating tumor cells
Circulating tumor cells (CTCs) have a great potential as indicators of metastatic disease that
may help physicians improve cancer prognostication, treatment and patient outcomes. …
may help physicians improve cancer prognostication, treatment and patient outcomes. …
Scaling biological discovery at the interface of deep learning and cellular imaging
…, E Pradhan, A Ates, D Gallandt, R Barnowski, E Pao… - Nature …, 2023 - nature.com
Concurrent advances in imaging technologies and deep learning have transformed the nature
and scale of data that can now be collected with imaging. Here we discuss the progress …
and scale of data that can now be collected with imaging. Here we discuss the progress …
Quantitative magnetic separation of particles and cells using gradient magnetic ratcheting
Extraction of rare target cells from biosamples is enabling for life science research. Traditional
rare cell separation techniques, such as magnetic activated cell sorting, are robust but …
rare cell separation techniques, such as magnetic activated cell sorting, are robust but …
Unsupervised capture and profiling of rare immune cells using multi-directional magnetic ratcheting
C Murray, H Miwa, M Dhar, DE Park, E Pao, J Martinez… - Lab on a Chip, 2018 - pubs.rsc.org
Immunotherapies (IT) require induction, expansion, and maintenance of specific changes to
a patient's immune cell repertoire which yield a therapeutic benefit. Recently, mechanistic …
a patient's immune cell repertoire which yield a therapeutic benefit. Recently, mechanistic …
Continuous and quantitative purification of T-cell subsets for cell therapy manufacturing using magnetic ratcheting cytometry
C Murray, E Pao, A Jann, DE Park… - SLAS TECHNOLOGY …, 2018 - journals.sagepub.com
… Edward Pao, and Dino Di Carlo hold equity in Ferrologix, Inc., which has licensed technology
described in this article. … Coleman Murray and Edward Pao contributed equally to this work. …
described in this article. … Coleman Murray and Edward Pao contributed equally to this work. …
Dynamic allocation of computational resources for deep learning-enabled cellular image analysis with Kubernetes
…, N Koe, D Kyme, T Kudo, B Chang, E Pao… - BioRxiv, 2018 - biorxiv.org
Deep learning is transforming the ability of life scientists to extract information from images.
These techniques have better accuracy than conventional approaches and enable …
These techniques have better accuracy than conventional approaches and enable …
[HTML][HTML] A Foundation Model for Cell Segmentation
Cells are the fundamental unit of biological organization, and identifying them in imaging
data-cell segmentation-is a critical task for various cellular imaging experiments. While deep …
data-cell segmentation-is a critical task for various cellular imaging experiments. While deep …