We present a modular approach for analyzing calcium imaging recordings of large neuronal
ensembles. Our goal is to simultaneously identify the locations of the neurons, demix …

Background Motion correction is a challenging pre-processing problem that arises early in
the analysis pipeline of calcium imaging data sequences. The motion artifacts in two-photon …

10.7554/eLife.38173.001 Advances in fluorescence microscopy enable monitoring larger
brain areas in-vivo with finer time resolution. The resulting data rates require reproducible …

10.7554/eLife.28728.001 In vivo calcium imaging through microendoscopic lenses enables
imaging of previously inaccessible neuronal populations deep within the brains of freely …

We developed a new way to engineer complex proteins toward multidimensional
specifications using a simple, yet scalable, directed evolution strategy. By robotically picking …

Recording the activity of large populations of neurons is an important step toward understanding
the emergent function of neural circuits. Here we present a simple holographic method …

Cerebellar granule cells, which constitute half the brain's neurons, supply Purkinje cells with
contextual information necessary for motor learning, but how they encode this information is …

The zebra finch brain features a set of clearly defined and hierarchically arranged motor
nuclei that are selectively responsible for producing singing behavior. One of these regions, a …

Hippocampal spiking sequences encode external stimuli and spatiotemporal intervals,
linking sequential experiences in memory, but the dynamics controlling the emergence and …

Inhibitory neurons, which play a critical role in decision-making models, are often simplified
as a single pool of non-selective neurons lacking connection specificity. This assumption is …