The ability of the brain to accurately control a movement depends on the cerebellum. Yet,
how the cerebellar neurons encode information relevant for this control remains poorly …

A common aspect of individuality is our subjective preferences in evaluation of reward and
effort. The neural circuits that evaluate these commodities influence circuits that control our …

Analysis of electrophysiological data from Purkinje cells (P-cells) of the cerebellum presents
unique challenges to spike sorting. Complex spikes have waveforms that vary significantly …

The common marmoset (Callithrix jacchus) is a promising new model for study of
neurophysiological basis of behavior in primates. Like other primates, it relies on saccadic eye …

Movement vigor, defined as the reciprocal of the latency from availability of reward to its
acquisition, changes with reward magnitude: movements exhibit shorter reaction time and …

Computations that are performed by the cerebellar cortex are transmitted via simple spikes
of Purkinje cells (P-cells) to downstream structures, but because P-cells are many synapses …

Learning from error is often a slow process. In machine learning, the learning rate depends
on a loss function that specifies a cost for error. Here, we hypothesized that during motor …

Our decisions are guided by how we perceive the value of an option, but this evaluation also
affects how we move to acquire that option. Why should economic variables such as reward …

… Ehsan Sedaghat-Nejad investigated the role of the oculomotor cerebellum in encoding
SPEs by recording Purkinje cell activity while marmosets performed saccades to a target …

It has been suggested that the central nervous system simplifies muscle control through basic
units, called synergies. In this study, we have developed a novel target-matching protocol …