PARASYMPATHETIC nerve stimulation causes slowing of the heart rate by activation of
muscarinic receptors and the subsequent opening of muscarinic K + channels in the sinoatrial …

ACETYLCHOLINE released during parasv mpathetic stimulation of the vagal nerve slows
the heart rate through the activation of muscarinic receptors and subsequent opening of an …

Both the α and βγ subunits of heterotrimeric guanine nucleotide–binding proteins (G proteins)
communicate signals from receptors to effectors. Gβγ subunits can regulate a diverse …

Store operated calcium entry (SOCE) is a principal cellular process by which cells regulate
basal calcium, refill intracellular Ca 2+ stores, and execute a wide range of specialized …

Activation of the tumor necrosis factor R1/Fas receptor results in the cleavage of cytosolic
BID to truncated tBID. tBID translocates to the mitochondria to induce the oligomerization of …

In heart, G-protein-activated channels are complexes of two homologous proteins, GIRK1
and GIRK4. Expression of either protein alone results in barely active or non-active channels, …

Aldosterone is the major corticosteroid regulating Na + absorption in tight epithelia and acts
primarily by activating the epithelial Na + channel (ENaC) through unknown induced proteins…

G protein-coupled inwardly rectifying potassium channels (GIRK/Kir3) are important elements
in controlling cellular excitability. In recent years, tremendous progress has been made …

1 The block of the IRK1/Kir2.1 inwardly rectifying K + channel by a Ba 2+ ion is highly voltage
dependent, where the ion binds approximately half‐way within the membrane electrical …

Phosphorylation of the epithelial Na + channel (ENaC) has been suggested to play a role in
its regulation. Here we demonstrate that phosphorylating the carboxyl termini of the β and γ …