Microglia and Parkinson's disease: footprints to pathology

E Lazdon, N Stolero, D Frenkel - Journal of Neural Transmission, 2020 - Springer
Parkinson's disease (PD) is a neurodegenerative disease associated with motor deficiency
and rigidity. The genetic risks of the disease is reported to be between 5 and 10% depending …

Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model

W Chen, Q Huang, EK Lazdon… - Proceedings of the …, 2023 - National Acad Sciences
Brain insulin signaling controls peripheral energy metabolism and plays a key role in the
regulation of mood and cognition. Epidemiological studies have indicated a strong connection …

From virus to diabetes therapy: Characterization of a specific insulin‐degrading enzyme inhibitor for diabetes treatment

…, K Pozyuchenko, L Sakhneny, E Lazdon… - The FASEB …, 2021 - Wiley Online Library
Inhibition of insulin‐degrading enzyme (IDE) is a possible target for treating diabetes.
However, it has not yet evolved into a medical intervention, mainly because most developed …

Astrocyte senescence in an Alzheimer's disease mouse model is mediated by TGF-β1 and results in neurotoxicity

S Amram, T Iram, E Lazdon, R Vassar, I Ben-Porath… - BioRxiv, 2019 - biorxiv.org
Alterations in astrocyte function such as a pro-inflammatory phenotype are associated with
Alzheimer’s disease (AD). We had shown impairments in the ability of aged astrocytes …

Investigating animal models of optic neuropathy: an accurate method for optic nerve and chiasm dissection in mice

…, K Shouchane-Blum, J Brody, E Lazdon… - Journal of Neuroscience …, 2020 - Elsevier
Background Numerous disorders affecting the optic nerve require histological examination of
whole length optic nerves and chiasm. Most methods employed to study the histopathology …

The Clinical Experience: A Case Analysis

RA Solomon - Seton Hall L. Rev., 1991 - HeinOnline
… 5 At one of our first meetings in 1986, we invited Douglas Lasdon from the Legal Action
Center for the Homeless in New York City. Lasdon told us that he took pride in starting every talk …

The Clinical Experience: A Case Analysis

R Solomon - 1992 - openyls.law.yale.edu
… 5 At one of our first meetings in 1986, we invited Douglas Lasdon from the Legal Action
Center for the Homeless in New York City. Lasdon told us that he took pride in starting every talk …

[BOOK][B] Glam!: An Eyewitness Account

M Rock - 2005 - books.google.com
“Glam was about make-up, mirrors and androgyny. It was narcissistic, obsessive, decadent
and subversive. It was bohemian, but also strangely futuristic. It was Oscar Wilde meets A …

The 1976 May Show: November 24, 1976, through January 2, 1977. Fifty-Seventh Annual Exhibition by Artists and Craftsmen of the Western Reserve

EB Henning - The Bulletin of the Cleveland Museum of Art, 1976 - JSTOR
It is difficult to avoid redundancy in the introduction to the May Show catalog. The show is
different each year, but certain charac teristics remain relatively stable. The show is simply the …

Developing hydrological and reservoir models under deep uncertainty of climate change: robustness of water supply reservoir

D Marton, K Knoppová - Water Supply, 2019 - iwaponline.com
Adaptation of water resources to climate change, drought management strategies, and
hydrological and reservoir modelling have become serious issues in the context of climate …