User profiles for Ekaterina Postovalova

Ekaterina Postovalova

Verified email at bostongene.com
Cited by 115

[HTML][HTML] Lack of intrafollicular memory CD4+ T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma

…, ZZ Yang, I Galkin, V Svelolkin, E Postovalova… - Blood cancer …, 2021 - nature.com
Despite a characteristic indolent course, a substantial subset of follicular lymphoma (FL)
patients has an early relapse with a poor outcome. Cells in the microenvironment may be a key …

A multi-scale, multiomic atlas of human normal and follicular lymphoma lymph nodes

AJ Radtke, E Postovalova, A Varlamova, A Bagaev… - BioRxiv, 2022 - biorxiv.org
Reference atlases, molecular and spatial maps of mammalian tissues, are critical resources
for discovery efforts and translational research. Their utility is dependent on operationalizing …

[HTML][HTML] TIGIT is a key inhibitory checkpoint receptor in lymphoma

…, Y Popov, C Jacobson, E Postovalova… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Background PD-1 checkpoint blockade therapy (CBT) has greatly benefited patients with
select solid tumors and lymphomas but has limited efficacy against diffuse large B-cell …

Single-cell spatial proteomic revelations on the multiparametric MRI heterogeneity of clinically significant prostate cancer

…, N Kotlov, A Ramachandran, E Postovalova… - Clinical Cancer …, 2021 - AACR
Purpose: Multiparametric MRI (mpMRI) has become an indispensable radiographic tool in
diagnosing prostate cancer. However, mpMRI fails to visualize approximately 15% of clinically …

Next-generation ALK inhibitors are highly active in ALK-positive large B-cell lymphoma

…, O Kudryashova, E Postovalova… - Blood, The Journal …, 2022 - ashpublications.org
Ekaterina Postovalova, Ekaterina Postovalova … Rimsza, Kurt Bantilan, Haley Martin, Matthew
Lei, Sydney Mohr, Anna Kurilovich, Olga Kudryashova, Ekaterina Postovalova, Valentina …

Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients

AJ Radtke, E Postovalova, A Varlamova, A Bagaev… - Cancer Cell, 2024 - cell.com
Follicular lymphoma (FL) is a generally incurable malignancy that evolves from developmentally
blocked germinal center (GC) B cells. To promote survival and immune escape, tumor B …

Spatial mapping of human hematopoiesis at single-cell resolution reveals aging-associated topographic remodeling

…, I Galkin, P Ovcharov, D Tabakov, E Postovalova… - Blood, 2023 - ashpublications.org
The spatial anatomy of hematopoiesis in the bone marrow (BM) has been extensively
studied in mice and other preclinical models, but technical challenges have precluded a …

A prospective study of clonal evolution in follicular lymphoma: circulating tumor DNA correlates with overall tumor burden and fluctuates over time without therapy

…, AP Jacob, A Bagaev, M Meerson, E Postovalova… - Blood, 2021 - ashpublications.org
Background: Follicular lymphoma (FL) shows marked variation in clinical course including
spontaneous regression and histologic transformation (HT). Watchful waiting (W&W) is …

[PDF][PDF] Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity

N Miheecheva, E Postovalova, Y Lyu… - Cell Reports, 2022 - cell.com
Intratumor heterogeneity (ITH) represents a major challenge for anticancer therapies. An
integrated, multidimensional, multiregional approach dissecting ITH of the clear cell renal cell …

[HTML][HTML] Hypoxia is a key mechanism for regulating inflammation in ulcerative colitis

EA Postovalova, OV Makarova… - … Open Medical Journal, 2020 - cyberleninka.ru
Intestinal bowel diseases (IBD), including ulcerative colitis (UC), is the group of difficult to
diagnose widespread among the population diseases. Pathogenesis of the disease is …