Thioester-containing proteins and insect immunity
S Blandin, EA Levashina - Molecular immunology, 2004 - Elsevier
Here, we discuss the role of thioester-containing proteins in innate immune responses of
insects. TEPs are represented by multi-member families both in the fruitfly, Drosophila …
insects. TEPs are represented by multi-member families both in the fruitfly, Drosophila …
[HTML][HTML] Reverse genetics in the mosquito Anopheles gambiae: targeted disruption of the Defensin gene
…, T Köcher, M Wilm, FC Kafatos, EA Levashina - EMBO …, 2002 - embopress.org
Anopheles gambiae, the major vector of human malaria parasite, is an important insect
model to study vector–parasite interactions. Here, we developed a simple in vivo double-…
model to study vector–parasite interactions. Here, we developed a simple in vivo double-…
[HTML][HTML] Antimalarial responses in Anopheles gambiae: from a complement-like protein to a complement-like pathway
SA Blandin, E Marois, EA Levashina - Cell host & microbe, 2008 - cell.com
Malaria transmission between humans depends on the ability of Anopheles mosquitoes to
support Plasmodium development. New perspectives in vector control are emerging from …
support Plasmodium development. New perspectives in vector control are emerging from …
Immunity-Related Genes and Gene Families in Anopheles gambiae
…, JA Hoffmann, SM Kanzok, I Letunic, EA Levashina… - Science, 2002 - science.org
We have identified 242 Anopheles gambiae genes from 18 gene families implicated in innate
immunity and have detected marked diversification relative to Drosophila melanogaster. …
immunity and have detected marked diversification relative to Drosophila melanogaster. …
Innate immune defense against malaria infection in the mosquito
G Dimopoulos, HM Müller, EA Levashina… - Current opinion in …, 2001 - Elsevier
Anopheles gambiae, the most important vector of malaria, employs its innate immune system
in the fight against Plasmodium. This can affect the propagative capacity of Plasmodium in …
in the fight against Plasmodium. This can affect the propagative capacity of Plasmodium in …
[HTML][HTML] Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae
Anopheles mosquitoes are major vectors of human malaria in Africa. Large variation exists
in the ability of mosquitoes to serve as vectors and to transmit malaria parasites, but the …
in the ability of mosquitoes to serve as vectors and to transmit malaria parasites, but the …
[HTML][HTML] Midgut Microbiota of the Malaria Mosquito Vector Anopheles gambiae and Interactions with Plasmodium falciparum Infection
…, PH Awono-Ambene, EA Levashina… - PLoS …, 2012 - journals.plos.org
The susceptibility of Anopheles mosquitoes to Plasmodium infections relies on complex
interactions between the insect vector and the malaria parasite. A number of studies have …
interactions between the insect vector and the malaria parasite. A number of studies have …
Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes
Mosquitoes are vectors of parasitic and viral diseases of immense importance for public
health. The acquisition of the genome sequence of the yellow fever and Dengue vector, Aedes …
health. The acquisition of the genome sequence of the yellow fever and Dengue vector, Aedes …
[HTML][HTML] Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae
We characterize a novel hemocyte-specific acute phase glycoprotein from the malaria vector,
Anopheles gambiae. It shows substantial structural and functional similarities, including the …
Anopheles gambiae. It shows substantial structural and functional similarities, including the …
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
EA Levashina, E Langley, C Green, D Gubb… - Science, 1999 - science.org
The antifungal defense of Drosophila is controlled by the spaetzle/Toll/cactus gene cassette.
Here, a loss-of-function mutation in the gene encoding a blood serine protease inhibitor, …
Here, a loss-of-function mutation in the gene encoding a blood serine protease inhibitor, …